Publication Name	World Journal of Gastroenterology
Manuscript ID	14607
Country	Mexico

Received	2014-10-15 08:29
Peer-Review Started	2014-10-15 12:20
To Make the First Decision	2014-11-14 19:03
Return for Revision	2014-11-18 14:45
Revised	2014-12-11 06:38
Second Decision	2015-02-11 22:51
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2015-02-12 17:28
Articles in Press	2015-02-13 11:19
Publication Fee Transferred
Edit the Manuscript by Language Editor	2015-03-06 16:45
Typeset the Manuscript	2015-03-20 11:08
Publish the Manuscript Online	2015-04-07 17:13

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright	© The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
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Website	http://www.wjgnet.com

Category	Gastroenterology & Hepatology
Manuscript Type	Review
Article Title	New gene therapy strategies for hepatic fibrosis
Manuscript Source	Invited Manuscript
All Author List	Adriana M Salazar-Montes, Luis D Hernández-Ortega, Martha S Lucano-Landeros and Juan Armendariz-Borunda
Funding Agency and Grant Number
Corresponding Author	Dr. Juan Armendáriz-Borunda, Department of Molecular Biology and Genomics, Institute for Molecular Biology and Gene Therapy, University of Guadalajara, Sierra Mojada 950, Guadalajara, Jalisco 44281, México. armdbo@gmail.com
Key Words	Gene therapy; Hepatic fibrosis; Viral vectors; Non-viral vectors
Core Tip	Cirrhosis is the irreversible end result of fibrous scarring and hepatocellular regeneration. Cirrhosis is a disease without effective treatment and new therapeutic strategies to accomplish healing are continuously being sought. Liver-based gene therapy has been used to improve liver function using viral and non-viral vectors. This review provides an overview of the main strategies used in liver-gene therapy, with the hope of finding a niche application in a given clinical scenario.
Publish Date	2015-04-07 17:13
Citation	Salazar-Montes AM, Hernández-Ortega LD, Lucano-Landeros MS, Armendariz-Borunda J. New gene therapy strategies for hepatic fibrosis. World J Gastroenterol 2015; 21(13): 3813-3825
URL	http://www.wjgnet.com/1007-9327/full/v21/i13/3813.htm
DOI	http://dx.doi.org/10.3748/wjg.v21.i13.3813

Full Article (PDF)	WJG-21-3813.pdf
Full Article (Word)	WJG-21-3813.doc
Manuscript File	14607-Review.docx
Answering Reviewers	14607-Answering reviewers.pdf
Copyright License Agreement	14607-Copyright assignment.pdf
Non-Native Speakers of English Editing Certificate	14607-Language certificate.pdf
Peer-review Report	14607-Peer-review(s).pdf
Scientific Misconduct Check	14607-Scientific misconduct check.pdf
Scientific Editor Work List	14607-Scientific editor work list.pdf