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Publication Name World Journal of Virology
Manuscript ID 14847
Country/Territory Brazil
2014-10-28 08:37
Peer-Review Started
2014-10-28 10:11
To Make the First Decision
2014-11-27 12:09
Return for Revision
2014-12-03 12:22
2015-01-15 20:10
Second Decision
2015-02-27 09:36
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2015-03-09 17:21
Articles in Press
2015-03-09 17:21
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2015-04-17 17:25
Publish the Manuscript Online
2015-04-30 17:58
ISSN 2220-3249 (online)
Open Access This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Infectious Diseases
Manuscript Type Review
Article Title Impact of antiretroviral therapy on lipid metabolism of human immunodeficiency virus-infected patients: Old and new drugs
Manuscript Source Invited Manuscript
All Author List Joel da Cunha, Luciana Morganti Ferreira Maselli, Ana Carolina Bassi Stern, Celso Spada and Sérgio Paulo Bydlowski
Funding Agency and Grant Number
Corresponding author Sérgio Paulo Bydlowski, MD, PhD, Associate Professor of Hematology, Director, Laboratory of Genetics and Molecular Hematology (LIM-31), University of São Paulo Medical School (FMUSP), Av. Dr. Enéas de Carvalho Aguiar, 155, 1 andar, Sala 43, São Paulo SP 05403-000, Brazil. spbydlow@usp.br
Keywords Human immunodeficiency virus-1 infection; Highly active antiretroviral therapy; Protease inhibitors; Dyslipidemia; Atherosclerosis; Lipodystrophy; Statins; Fibrates; Diet; Lifestyle
Core Tip Antiretroviral therapy inhibits human im?munodeficiency virus (HIV)-1 replication, reduces mortality and increases survival. On the other hand, HIV-1 infection and antiretroviral therapy affect lipid metabolism. In fact, lipodystrophy is a well-documented side effect of highly active antiretroviral therapy (HAART). Switching to a less metabolically active drug improve HAART-associated dyslipidemia. Other therapies may include statins, fibrates, inhibitors cholesterol absorption, fish oils, niacin. Moreover, changes in diet and lifestyle are needed to revert the dyslipidemia.
Publish Date 2015-04-30 17:58
Citation da Cunha J, Maselli LMF, Stern ACB, Spada C, Bydlowski SP. Impact of antiretroviral therapy on lipid metabolism of human immunodeficiency virus-infected patients: Old and new drugs. World J Virol 2015; 4(2): 56-77
Url http://www.wjgnet.com/2220-3249/full/v4/i2/56.htm
DOI http://dx.doi.org/10.5501/wjv.v4.i2.56
Full Article (PDF) WJV-4-56.pdf
Full Article (Word) WJV-4-56.doc
Manuscript File 14847-Review.docx
Answering Reviewers 14847-Answering reviewers.pdf
Conflict-of-Interest Disclosure Form 14847-Conflict-of-interest statement.pdf
Copyright License Agreement 14847-Copyright assignment.pdf
Non-Native Speakers of English Editing Certificate 14847-Language certificate.pdf
Peer-review Report 14847-Peer-review(s) .pdf
Scientific Misconduct Check 14847-Scientific misconduct check.pdf
Scientific Editor Work List 14847-Scientific editor work list.pdf