Publication Name	World Journal of Virology
Manuscript ID	14877
Country	United States

Received	2014-10-29 09:02
Peer-Review Started	2014-11-06 20:39
To Make the First Decision	2014-12-12 17:28
Return for Revision	2014-12-16 12:20
Revised	2015-01-23 01:10
Second Decision	2015-02-03 19:42
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2015-02-11 15:55
Articles in Press	2015-02-11 15:55
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2015-04-17 17:24
Publish the Manuscript Online	2015-04-30 17:58

ISSN	2220-3249 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright	© The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
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Category	Neurosciences
Manuscript Type	Review
Article Title	New advances on glial activation in health and disease
Manuscript Source	Invited Manuscript
All Author List	Kim Mai Lee and Andrew G MacLean
Funding Agency and Grant Number
Corresponding Author	Andrew G MacLean, PhD, Assistant Professor, Department of Microbiology and Immunology, Division of Comparative Pathology, Tulane University School of Medicine, 18703 Three Rivers Road, Covington, LA 70433, United States. amaclean@tulane.edu
Key Words	Astrocyte; Microglia; Neuroinflammation; Aging; Alzheimer’s; Neurodegeneration
Core Tip	Over the past decade, research has begun to elucidate the role of astrocyte activation and changes in astrocyte morphology in the progression of neural pathologies, which has led to glial-specific interventions for drug development. This review addresses astrocyte response to central nervous system (CNS) injury and disease in relation to astrocyte activation, immune response, and changes in morphology. Further discussion addresses potential therapeutics targeting astrocytes, which consider these heterogeneous responses to CNS insults.
Publish Date	2015-04-30 17:58
Citation	Lee KM, MacLean AG. New advances on glial activation in health and disease. World J Virol 2015; 4(2): 42-55
URL	http://www.wjgnet.com/2220-3249/full/v4/i2/42.htm
DOI	http://dx.doi.org/10.5501/wjv.v4.i2.42

Full Article (PDF)	WJV-4-42.pdf
Full Article (Word)	WJV-4-42.doc
Manuscript File	14877-Review.docx
Answering Reviewers	14877-Answering reviewers.pdf
Conflict-of-Interest Disclosure Form	14877-Conflict-of-interest statement.pdf
Copyright License Agreement	14877-Copyright assignment.pdf
Peer-review Report	14877-Peer-review(s).pdf
Scientific Misconduct Check	14877-Scientific misconduct check.pdf
Scientific Editor Work List	14877-Scientific editor work list.pdf