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Articles Published Processes
4/15/2015 11:01:00 AM | Browse: 1107 | Download: 2216
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Received |
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2014-11-11 09:38 |
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Peer-Review Started |
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2014-11-12 11:38 |
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To Make the First Decision |
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2014-12-11 20:28 |
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Return for Revision |
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2014-12-16 17:51 |
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Revised |
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2015-01-11 23:18 |
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Second Decision |
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2015-01-29 12:31 |
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Accepted by Journal Editor-in-Chief |
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2015-01-30 16:58 |
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Accepted by Executive Editor-in-Chief |
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2015-02-05 17:22 |
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Articles in Press |
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2015-02-05 17:44 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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2015-02-22 00:34 |
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Typeset the Manuscript |
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2015-03-31 17:35 |
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Publish the Manuscript Online |
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2015-04-15 11:01 |
| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Biochemical Research Methods |
| Manuscript Type |
Prospective Study |
| Article Title |
Arpin contributes to bacterial translocation and development of severe acute pancreatitis
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Wen-Sheng Deng, Jian Zhang, Hui Ju, Hong-Mei Zheng, Jiang Wang, Su Wang and Dian-Liang Zhang |
| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| Natural Science Foundation of China |
81270448 |
| Natural Science Foundation of China |
81470890 |
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| Corresponding Author |
Dian-Liang Zhang, MD, PhD, Center of Colon and Rectum, Qingdao Municipal Hospital, Qingdao University, No. 16 Jiangsu Road, Qingdao 266011, Shandong Province, China. phdzdl@yahoo.com |
| Key Words |
Severe acute pancreatitis; Arpin; Tight junction proteins; Bacterial translocation; Epithelium; Intestinal epithelial barrier |
| Core Tip |
Tight junctions (TJs) are the structural basis for the intestinal epithelial barrier. Increased intestinal permeability caused by variations in TJ proteins may result in bacterial translocation (BT) and there is evidence that BT may contribute to infection and sepsis. However, the detailed mechanisms for BT remain unknown. Recent work has identified an Arp2/3 interacting protein called Arpin, which was shown to restrict the rate of actin polymerization and control cell migration. Our research shows that Arpin protein affects the expression of TJ proteins and may have an impact on BT. |
| Publish Date |
2015-04-15 11:01 |
| Citation |
Deng WS, Zhang J, Ju H, Zheng HM, Wang J, Wang S, Zhang DL. Arpin contributes to bacterial translocation and development of severe acute pancreatitis. World J Gastroenterol 2015; 21(14): 4293-4301 |
| URL |
http://www.wjgnet.com/1007-9327/full/v21/i14/4293.htm |
| DOI |
http://dx.doi.org/10.3748/wjg.v21.i14.4293 |
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