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4/27/2015 4:29:00 PM | Browse: 539 | Download: 727
Publication Name World Journal of Gastroenterology
Manuscript ID 15194
Country/Territory China
Received
2014-11-13 18:52
Peer-Review Started
2014-11-15 16:18
To Make the First Decision
2014-12-02 09:20
Return for Revision
2014-12-04 10:46
Revised
2014-12-09 15:50
Second Decision
2015-01-29 12:34
Accepted by Journal Editor-in-Chief
2015-01-29 15:34
Accepted by Company Editor-in-Chief
2015-02-05 17:24
Articles in Press
2015-02-05 17:44
Publication Fee Transferred
Edit the Manuscript by Language Editor
2015-03-16 05:02
Typeset the Manuscript
2015-04-15 13:44
Publish the Manuscript Online
2015-04-27 16:22
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology and Hepatology
Manuscript Type Clinical Trials Study
Article Title Moxibustion combined with acupuncture increases tight junction protein expression in Crohn’s disease patients
Manuscript Source Unsolicited Manuscript
All Author List Hai-Xia Shang, An-Qi Wang, Chun-Hui Bao, Huan-Gan Wu, Wei-Feng Chen, Lu-Yi Wu, Rong Ji, Ji-Meng Zhao and Yin Shi
Funding Agency and Grant Number
Funding Agency Grant Number
National Natural Science Foundation of China 30772831
National Natural Science Foundation of China 81473757
National Basic Research Program of China(973 Program) 2009CB522900
Corresponding author Yin Shi, MD, PhD, Shanghai Institute of Acupuncture-Moxibustion and Meridian, No. 650 South Wanping Road, Xuhui District, Shanghai 200030, China. flysy0636@163.com
Keywords Crohn’s disease; Herb-partitioned moxibustion; Acupuncture; Intestinal epithelial cells; Tight junction proteins
Core Tip Crohn’s disease (CD) is a chronic relapsing inflammatory condition involving all layers of the gastrointestinal tract. Although its etiopathogenesis remains unclear, increased permeability of the intestinal epithelial barrier is one of the crucial factors in CD onset. Tight junctions (TJs) within intestinal epithelial cells form the structural basis of the intestinal epithelial barrier, and reduced expression of TJ proteins is positively correlated with CD severity. This study investigated the therapeutic effect of herb-partitioned moxibustion combined with acupuncture on CD. We found that this treatment upregulated the expression of intestinal epithelial TJ proteins and their mRNAs.
Publish Date 2015-04-27 16:22
Citation Shang HX, Wang AQ, Bao CH, Wu HG, Chen WF, Wu LY, Ji R, Zhao JM, Shi Y. Moxibustion combined with acupuncture increases tight junction protein expression in Crohn’s disease patients. World J Gastroenterol 2015; 21(16): 4986-4996
Url http://www.wjgnet.com/1007-9327/full/v21/i16/4986.htm
DOI http://dx.doi.org/10.3748/wjg.v21.i16.4986
Full Article (PDF) WJG-21-4986.pdf
Full Article (Word) WJG-21-4986.doc
Manuscript File 15194-Review.docx
Answering Reviewers 15194-Answering reviewers.pdf
Copyright License Agreement 15194-Copyright assignment.pdf
Institutional Review Board Approval Form or Document Ethics_Committee_20141113104919.jpg
Non-Native Speakers of English Editing Certificate 15194-Language certificate.pdf
Peer-review Report 15194-Peer-review(s).pdf
Journal Editor-in-Chief Review Report 15194-Journal Editor-in-Chief's Review Report.pdf
Scientific Misconduct Check 15194-Scientific misconduct check.pdf
Scientific Editor Work List 15194-Scientific editor work list.pdf