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Articles Published Processes
4/27/2015 4:29:00 PM | Browse: 1410 | Download: 1861
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Received |
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2014-11-13 18:52 |
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Peer-Review Started |
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2014-11-15 16:18 |
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To Make the First Decision |
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2014-12-02 09:20 |
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Return for Revision |
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2014-12-04 10:46 |
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Revised |
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2014-12-09 15:50 |
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Second Decision |
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2015-01-29 12:34 |
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Accepted by Journal Editor-in-Chief |
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2015-01-29 15:34 |
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Accepted by Executive Editor-in-Chief |
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2015-02-05 17:24 |
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Articles in Press |
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2015-02-05 17:44 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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2015-03-16 05:02 |
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Typeset the Manuscript |
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2015-04-15 13:44 |
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Publish the Manuscript Online |
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2015-04-27 16:22 |
ISSN |
1007-9327 (print) and 2219-2840 (online) |
Open Access |
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
Copyright |
© The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
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Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
Website |
http://www.wjgnet.com |
Category |
Gastroenterology & Hepatology |
Manuscript Type |
Clinical Trials Study |
Article Title |
Moxibustion combined with acupuncture increases tight junction protein expression in Crohn’s disease patients
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Manuscript Source |
Unsolicited Manuscript |
All Author List |
Hai-Xia Shang, An-Qi Wang, Chun-Hui Bao, Huan-Gan Wu, Wei-Feng Chen, Lu-Yi Wu, Rong Ji, Ji-Meng Zhao and Yin Shi |
Funding Agency and Grant Number |
Funding Agency |
Grant Number |
National Natural Science Foundation of China |
30772831 |
National Natural Science Foundation of China |
81473757 |
National Basic Research Program of China(973 Program) |
2009CB522900 |
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Corresponding Author |
Yin Shi, MD, PhD, Shanghai Institute of Acupuncture-Moxibustion and Meridian, No. 650 South Wanping Road, Xuhui District, Shanghai 200030, China. flysy0636@163.com |
Key Words |
Crohn’s disease; Herb-partitioned moxibustion; Acupuncture; Intestinal epithelial cells; Tight junction proteins |
Core Tip |
Crohn’s disease (CD) is a chronic relapsing inflammatory condition involving all layers of the gastrointestinal tract. Although its etiopathogenesis remains unclear, increased permeability of the intestinal epithelial barrier is one of the crucial factors in CD onset. Tight junctions (TJs) within intestinal epithelial cells form the structural basis of the intestinal epithelial barrier, and reduced expression of TJ proteins is positively correlated with CD severity. This study investigated the therapeutic effect of herb-partitioned moxibustion combined with acupuncture on CD. We found that this treatment upregulated the expression of intestinal epithelial TJ proteins and their mRNAs. |
Publish Date |
2015-04-27 16:22 |
Citation |
Shang HX, Wang AQ, Bao CH, Wu HG, Chen WF, Wu LY, Ji R, Zhao JM, Shi Y. Moxibustion combined with acupuncture increases tight junction protein expression in Crohn’s disease patients. World J Gastroenterol 2015; 21(16): 4986-4996 |
URL |
http://www.wjgnet.com/1007-9327/full/v21/i16/4986.htm |
DOI |
http://dx.doi.org/10.3748/wjg.v21.i16.4986 |
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