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Articles Published Processes
9/16/2014 1:19:00 PM | Browse: 1188 | Download: 1020
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Received |
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2012-12-18 21:07 |
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Peer-Review Started |
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2012-12-19 14:53 |
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To Make the First Decision |
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2012-12-27 12:21 |
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Return for Revision |
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2012-12-28 09:21 |
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Revised |
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2013-01-01 14:56 |
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Second Decision |
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2013-02-06 11:30 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2013-02-06 12:13 |
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Articles in Press |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2013-03-27 09:10 |
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Publish the Manuscript Online |
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2013-04-09 16:03 |
Category |
Surgery |
Manuscript Type |
Autobiography |
Article Title |
Clinicopathological and prognostic significance of galectin-1 and vascular endothelial growth factor expression in gastric cancer
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Manuscript Source |
Invited Manuscript |
All Author List |
Jie Chen, Su-Jun Zhou, Yun Zhang, Guo-Qiang Zhang, Tian-Zhou Zha, Yi-Zhong Feng and Kai Zhang |
Funding Agency and Grant Number |
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Corresponding Author |
Kai Zhang, MD, Department of General Surgery, Yixing People's Hospital, the Affiliated Hospital of Jiangsu University, No. 75, Tongzhen Guan Road, Yixing 214200, Jiangsu Province, China. yxphpwk@163.com
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Key Words |
Galectin-1; Vascular endothelial growth factor; Gastric cancer; Prognosis |
Core Tip |
Galectin-1 and vascular endothelial growth factor (VEGF) played important roles in angiogenesis and progression of malignant tumor, while their expression in Chinese gastric cancer and relationship between the two parameters and clinicopathological features, as well as prognostic value remained largely unknown. In this present study, we examined 214 gastric cancer samples for the presence of galectin-1 oncoprotein and VEGF by immunohistochemistry and found that overexpressions of galectin-1 and VEGF were related with tumor progression and poor survival, and our findings supported an association between galectin-1 and VEGF expression. These two molecules may serve as independent predicative markers for patient prognosis in gastric cancer.
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Publish Date |
2013-04-09 16:03 |
Citation |
Chen J, Zhou SJ, Zhang Y, Zhang GQ, Zha TZ, Feng YZ, Zhang K. Clinicopathological and prognostic significance of galectin-1 and vascular endothelial growth factor expression in gastric cancer. World J Gastroenterol 2013; 19(13): 2073-2079 |
URL |
http://www.wjgnet.com/1007-9327/full/v19/i13/2073.htm |
DOI |
http://dx.doi.org/10.3748/wjg.v19.i13.2073 |
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