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Articles Published Processes
4/7/2015 6:08:00 PM | Browse: 1476 | Download: 1612
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Received |
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2014-11-28 08:23 |
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Peer-Review Started |
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2014-11-28 09:19 |
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To Make the First Decision |
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2014-12-26 13:22 |
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Return for Revision |
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2014-12-31 09:15 |
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Revised |
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2015-01-09 00:10 |
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Second Decision |
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2015-02-11 22:58 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2015-02-13 10:36 |
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Articles in Press |
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2015-02-13 11:29 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2015-03-23 14:38 |
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Publish the Manuscript Online |
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2015-04-07 17:13 |
| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Cell Biology |
| Manuscript Type |
Editorial |
| Article Title |
Field cancerisation in colorectal cancer: A new frontier or pastures past?
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Abhilasha Patel, Gyanendra Tripathi, Kishore Gopalakrishnan, Nigel Williams and Ramesh P Arasaradnam |
| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| Bowel Disease Research Foundation, United Kingdom |
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| Corresponding Author |
Abhilasha Patel, Research Registrar, Department of Colorectal Surgery, University Hospitals of Coventry and Warwickshire NHS Trust, Clifford Bridge Road, Coventry CV2 2DX, United Kingdom. abhilasha.patel@doctors.org.uk |
| Key Words |
Colorectal cancer; Carcinogenesis; Biomarkers; Epigenetics; Synchronous |
| Core Tip |
There is a great deal of interest in developing non- invasive tests that are able to detect colorectal cancer in the asymptomatic population. Most current research activity is focussed on investigating the biological changes found in tumour tissue itself. This review evaluates the biological alterations found in the normal mucosa around a neoplastic lesion and critically analyses the concept of field cancerisation. It highlights recent advances and identifies important molecular targets that could play a role in early colorectal carcinogenesis. In particular, the available evidence for field cancerisation is scrutinised and future avenues for further scientific enquiry are outlined. |
| Publish Date |
2015-04-07 17:13 |
| Citation |
Patel A, Tripathi G, Gopalakrishnan K, Williams N, Arasaradnam RP. Field cancerisation in colorectal cancer: A new frontier or pastures past? World J Gastroenterol 2015; 21(13): 3763-3772 |
| URL |
http://www.wjgnet.com/1007-9327/full/v21/i13/3763.htm |
| DOI |
http://dx.doi.org/10.3748/wjg.v21.i13.3763 |
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