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5/20/2015 5:01:00 PM | Browse: 844 | Download: 1602
Publication Name World Journal of Gastroenterology
Manuscript ID 15907
Country/Territory China
Received
2014-12-16 11:41
Peer-Review Started
2014-12-16 15:05
To Make the First Decision
2015-01-08 16:54
Return for Revision
2015-01-13 08:45
Revised
2015-01-15 15:15
Second Decision
2015-02-11 23:01
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2015-02-13 11:06
Articles in Press
2015-02-13 11:31
Publication Fee Transferred
Edit the Manuscript by Language Editor
2015-04-02 15:48
Typeset the Manuscript
2015-05-08 19:00
Publish the Manuscript Online
2015-05-20 17:01
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Oncology
Manuscript Type Basic Study
Article Title miR-451 inhibits proliferation of esophageal carcinoma cell line EC9706 by targeting CDKN2D and MAP3K1
Manuscript Source Unsolicited Manuscript
All Author List Wen-Qiao Zang, Xuan Yang, Tao Wang, Yuan-Yuan Wang, Yu-Wen Du, Xiao-Nan Chen, Min Li and Guo-Qiang Zhao
Funding Agency and Grant Number
Funding Agency Grant Number
National Natural Science Foundation of China 81301726
Corresponding Author Guo-Qiang Zhao, PhD, College of Basic Medical Sciences, Zhengzhou University, 40 Daxue North Road, 450001 Zhengzhou, Henan Province, China. zhaogq@zzu.edu.cn
Key Words Esophageal squamous cell carcinoma; miR-451; CDKN2D; MAP3K1; Proliferation
Core Tip Recently miR-451 has been reported to be tumor suppressor in human cancer cells. In the previous studies we have reported that miR-451expression in esophageal squamous cell carcinoma (ESCC) tissues was significantly reduced, and that upregulated expression of miR-451 induced apoptosis and suppressed cell proliferation, invasion and metastasis in the esophageal carcinoma. However, the underlying molecular mechanisms remain unclear. In this study, we supposed and showed that CDKN2D and MAP3K1 were the targets of miR-451by the bioinformatics algorithms (TargetScan and miRBase), moreover, CDKN2D and MAP3K1 contributed to ESCC malignancy.
Publish Date 2015-05-20 17:01
Citation Zang WQ, Yang X, Wang T, Wang YY, Du YW, Chen XN, Li M, Zhao GQ. MiR-451 inhibits proliferation of esophageal carcinoma cell line EC9706 by targeting CDKN2D and MAP3K1. World J Gastroenterol 2015; 21(19): 5867-5876
URL http://www.wjgnet.com/1007-9327/full/v21/i19/5867.htm
DOI http://dx.doi.org/10.3748/wjg.v21.i19.5867
Full Article (PDF) WJG-21-5867.pdf
Full Article (Word) WJG-21-5867.doc
Manuscript File 15907-Review.docx
Answering Reviewers 15907-Answering reviewers.pdf
Audio Core Tip 15907-Audio core tip.mp3
Biostatistics Review Certificate 15907-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form 15907-Conflict-of-interest statement.pdf
Copyright License Agreement 15907-Copyright assignment.pdf
Institutional Animal Care and Use Committee Approval Form or Document 15907-Institutional animal care and use committee statement.pdf
Institutional Review Board Approval Form or Document 15907-Institutional review board statement.pdf
Peer-review Report 15907-Peer-review(s).pdf
Scientific Misconduct Check 15907-Scientific misconduct check.pdf
Scientific Editor Work List 15907-Scientific editor work list.pdf