Publication Name	World Journal of Gastroenterology
Manuscript ID	1599
Country	United States

Received	2012-12-22 05:42
Peer-Review Started	2012-12-22 15:32
To Make the First Decision	2013-01-09 15:54
Return for Revision	2013-01-10 15:34
Revised
Second Decision	2013-02-07 09:07
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2013-02-07 10:14
Articles in Press
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2013-03-31 10:50
Publish the Manuscript Online	2013-04-14 19:05

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access
Copyright
Article Reprints	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Pediatrics
Manuscript Type	Autobiography
Article Title	Aggressive juvenile polyposis in children with chromosome 10q23 deletion
Manuscript Source	Invited Manuscript
All Author List	Seth Septer, Lei Zhang, Caitlin E Lawson, Jose Cocjin, Thomas Attard and Holly H Ardinger
Funding Agency and Grant Number
Corresponding Author	Dr. Seth Septer, Department of Gastroenterology and Hepatology, Children's Mercy Hospital and Clinics, 2401 Gillham Road, Kansas City, MO 64108, United States. ssepter@cmh.edu
Key Words	Polyposis; Genetics; Cancer; Endoscopy pediatric
Core Tip	Children with aggressive juvenile polyposis related to microdeletions of chromosome 10q23 and involving PTEN and BMPR1A are rare, however this deletion conveys significant gastrointestinal and extraintestinal risks. Children with this gene mutation are at significant risk for extensive polyposis, early colectomy and gastrointestinal malignancy. This work describes the clinical manifestations associated with these deletions. We also suggest genetic testing strategies for those with juvenile polyps and also propose gastrointestinal surveillance for patients with chromosome 10q23 deletions encompassing PTEN and BMPR1A.
Publish Date	2013-04-14 19:05
Citation	Septer S, Zhang L, Lawson CE, Cocjin J, Attard T, Ardinger HH. Aggressive juvenile polyposis in children with chromosome 10q23 deletion. World J Gastroenterol 2013; 19(14): 2286-2292
URL	http://www.wjgnet.com/1007-9327/full/v19/i14/2286.htm
DOI	http://dx.doi.org/10.3748/wjg.v19.i14.2286

Full Article (PDF)	WJG-19-2286.pdf
Manuscript File	1599-Review.docx
Answering Reviewers	1599-Answering reviewers.pdf
Copyright License Agreement	1599-Copyright assignment.pdf
Peer-review Report	1599-Peer reviews.docx
Scientific Editor Work List	1599-Scientific editor work list.doc