Publication Name	World Journal of Gastroenterology
Manuscript ID	1616
Country	Netherlands

Received	2012-12-23 22:41
Peer-Review Started	2012-12-24 16:14
To Make the First Decision	2013-01-09 15:54
Return for Revision	2013-01-23 20:54
Revised
Second Decision	2013-03-22 12:05
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2013-03-23 09:33
Articles in Press
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2013-07-09 19:14
Publish the Manuscript Online	2013-07-20 20:47

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access
Copyright
Article Reprints	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Gastroenterology & Hepatology
Manuscript Type	Autobiography
Article Title	Low rates of adherence for tumor necrosis factor-α inhibitors in Crohn’s disease and rheumatoid arthritis: Results of a systematic review
Manuscript Source	Invited Manuscript
All Author List	Herma H Fidder, Maartje MJ Singendonk, Mike van der Have, Bas Oldenburg and Martijn GH van Oijen
Funding Agency and Grant Number
Corresponding Author	Herma H Fidder, MD, PhD, Department of Gastroenterology and Hepatology, University Medical Center Utrecht, PO Box 85500 (internal code F02.618), 3508 GA Utrecht, The Netherlands. h.fidder@umcutrecht.nl
Key Words	Adherence; Tumor necrosis factor- inhibitors; Systematic review; Crohn’s disease; Rheumatoid arthritis
Core Tip	This study assessed adherence with tumor necrosis factor-α (TNF-α) inhibitors in Crohn’s disease (CD) and rheumatoid arthritis (RA) by systematic review. We found only two-third of the patients with CD and RA receiving TNF-α inhibitors adherent to therapy. Definitions of measurement of adherence varied widely between studies and there is no clarity on what levels of adherence are required for optimal results of therapy. Future research on adherence should focus on therapy outcome, by using uniform definitions of adherence.
Publish Date	2013-07-20 20:47
Citation	Fidder HH, Singendonk MMJ, van der Have M, Oldenburg B, van Oijen MGH. Low rates of adherence for tumor necrosis factor-α inhibitors in Crohn’s disease and rheumatoid arthritis: Results of a systematic review. World J Gastroenterol 2013; 19(27): 4344-4350
URL	http://www.wjgnet.com/1007-9327/full/v19/i27/4344.htm
DOI	http://dx.doi.org/10.3748/wjg.v19.i27.4344

Full Article (PDF)	WJG-19-4344.pdf
Manuscript File	1616-Review.docx
Answering Reviewers	1616-Answering reviewers.docx
Copyright License Agreement	1616-Copyright assignment.pdf
Peer-review Report	1616-Peer reviewer(s).pdf
Scientific Editor Work List	1616-Scientific editor work list.doc