| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
|
| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Clinical Trials Study |
| Article Title |
Prevalence, significance and predictive value of antiphospholipid antibodies in Crohn’s disease
|
| Manuscript Source |
Invited Manuscript |
| All Author List |
Nora Sipeki, Laszlo Davida, Eszter Palyu, Istvan Altorjay, Jolan Harsfalvi, Peter Antal Szalmas, Zoltan Szabo, Gabor Veres, Zakera Shums, Gary L Norman, Peter L Lakatos and Maria Papp |
| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| Janos Bolyai Research Scholarship of the Hungarian Academy of Sciences |
|
| Internal Research Grant of University of Debrecen and the IOIBD Research Grant |
|
|
| Corresponding Author |
Maria Papp, MD, PhD, Division of Gastroenterology, Department of Internal Medicine, Faculty of Medicine, University of Debrecen, Nagyerdei krt. 98, H-4032 Debrecen, Hungary. papp.maria@med.unideb.hu |
| Key Words |
Crohn’s disease; Ulcerative colitis; Disease progression; Antiphospholipid antibodies; Anti-β2-Glycoprotein-I antibodies; Anti-phosphatidylserine/prothrombin; Anti-cardiolipin antibodies; Thrombosis |
| Core Tip |
Enhanced serological antibody formation is a well-known feature of inflammatory bowel diseases. Antiphospholipid antibodies (APLAs) are a prothrombotic group of antibodies acquired in various inflammatory diseases. However their association with clinical phenotype and disease progression is still unclear in inflammatory bowel diseases (IBD). In the present study we report enhanced formation of APLAs in patients with Crohn’s disease, which was not associated with clinical phenotype or disease course during follow-up in a tertiary referral IBD center from Hungary. |
| Publish Date |
2015-06-18 17:32 |
| Citation |
Sipeki N, Davida L, Palyu E, Altorjay I, Harsfalvi J, Antal Szalmas P, Szabo Z, Veres G, Shums Z, Norman GL, Lakatos PL, Papp M. Prevalence, significance and predictive value of antiphospholipid antibodies in Crohn’s disease. World J Gastroenterol 2015; 21(22): 6952-6964 |
| URL |
http://www.wjgnet.com/1007-9327/full/v21/i22/6952.htm |
| DOI |
http://dx.doi.org/10.3748/wjg.v21.i22.6952 |
