| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Case Report |
| Article Title |
Intraductal papillary neoplasm of the bile duct accompanying biliary mixed adenoneuroendocrine carcinoma
|
| Manuscript Source |
Invited Manuscript |
| All Author List |
Ichiro Onishi, Hirohisa Kitagawa, Kenichi Harada, Syogo Maruzen, Seisyo Sakai, Isamu Makino, Hironori Hayashi, Hisatoshi Nakagawara, Hidehiro Tajima, Hiroyuki Takamura, Takashi Tani, Masato Kayahara, Hiroko Ikeda, Tetsuo Ohta and Yasuni Nakanuma |
| Funding Agency and Grant Number |
|
| Corresponding Author |
Ichiro Onishi, MD, PhD, Department of Gastroenterologic Surgery, Graduate School of Medical Science, Kanazawa University, 13-1 Takara-machi, Kanazawa 920-8641, Japan. ionishi@kinbyou.hosp.go.jp
|
| Key Words |
Neuroendocrine tumor; Intraductal papillary neoplasm of bile duct; Intraductal papillary neoplasm of the bile duct; Bile duct |
| Core Tip |
A 74-year-old woman presented with fever and jaundice. Computed tomography revealed a polypoid tumor in the dilated distal bile duct. Pylorus-preserving pancreaticoduodenectomy was performed. Pathological examination revealed the papillary proliferation of biliary-type cells with nuclear atypia in the dilated bile duct, indicating papillary neoplasm of the bile duct. A solid portion comprised of tumor cells with characteristic salt-and-pepper nuclei was found. Immunohistochemistry revealed synaptophysin expression in the solid portion, diagnosing it as a neuroendocrine tumor (NET). This case provides insight into the pathogenesis of biliary NET.
|
| Publish Date |
2013-05-28 09:36 |
| Citation |
Onishi I, Kitagawa H, Harada K, Maruzen S, Sakai S, Makino I, Hayashi H, Nakagawara H, Tajima H, Takamura H, Tani T, Kayahara M, Ikeda H, Ohta T, Nakanuma Y. Intraductal papillary neoplasm of the bile duct accompanying biliary mixed adenoneuroendocrine carcinoma. World J Gastroenterol 2013; 19(20): 3161-3164 |
| URL |
http://www.wjgnet.com/1007-9327/full/v19/i20/3161.htm |
| DOI |
http://dx.doi.org/10.3748/wjg.v19.i20.3161 |
