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9/25/2015 5:30:00 PM | Browse: 488 | Download: 835
Publication Name World Journal of Stem Cells
Manuscript ID 16591
Country/Territory India
Received
2015-01-24 12:42
Peer-Review Started
2015-01-24 13:47
To Make the First Decision
2015-03-06 10:12
Return for Revision
2015-03-15 19:21
Revised
2015-06-27 00:00
Second Decision
2015-07-15 17:26
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2015-08-21 16:22
Articles in Press
2015-08-21 16:22
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2015-09-11 10:11
Publish the Manuscript Online
2015-09-25 17:30
ISSN 1948-0210 (online)
Open Access This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Oncology
Manuscript Type Editorial
Article Title Emerging role of microRNAs in cancer stem cells: Implications in cancer therapy
Manuscript Source Invited Manuscript
All Author List Minal Garg
Funding Agency and Grant Number
Corresponding author Minal Garg, Msc, PhD, Assistant Professor, Department of Biochemistry, University of Lucknow, University Road, Lucknow 226007, India. minal14@yahoo.com
Keywords Cancer stem cells; Drug resistance; Tumor recurrence; MicroRNAs; Cancer therapy
Core Tip Cancer stem cells (CSCs) which are believed to be the prerequisite for metastasis and tumor recurrence, are endowed with ability to undergo symmetric cell division, capacity for self-renewability, long term proliferation and resistance to anti-neoplasic therapeutic drugs. Regulatory characteristics of microRNAs (miRNAs) which are the clusters of non-coding RNA molecules, include widespread changes in gene expression through gene silencing at post-transcriptional level and are dysregulated in human cancer. Over the past two decades, miRNAs have gained widespread attention due to their involvement in acquisition of stem cell-like properties, regulation and reprogramming by cancer cells during cancer progression. Many studies are coming up which document miRNAs as novel therapeutic tool in targeting CSCs functions, sensitizing them to apoptotic effects of anti-cancer drugs, and reducing tumor burden with no relapse in current clinical settings.
Publish Date 2015-09-25 17:30
Citation Garg M. Emerging role of microRNAs in cancer stem cells: Implications in cancer therapy. World J Stem Cells 2015; 7(8): 1078-1089
Url http://www.wjgnet.com/1948-0210/full/v7/i8/1078.htm
DOI http://dx.doi.org/10.4252/wjsc.v7.i8.1078
Full Article (PDF) WJSC-7-1078.pdf
Full Article (Word) WJSC-7-1078.doc
Manuscript File 16591-Review.docx
Answering Reviewers 16591-Answering reviewers.pdf
Audio Core Tip 16591-Audio core tip.mp3
Conflict-of-Interest Disclosure Form 16591-Conflict-of-interest statement.pdf
Copyright License Agreement 16591-Copyright assignment.pdf
Peer-review Report 16591-Peer-review(s).pdf
Journal Editor-in-Chief Review Report 16591-Journal editor-in-chief review report.pdf
Scientific Misconduct Check 16591-Scientific misconduct check.pdf
Scientific Editor Work List 16591-Scientific editor work list.pdf