Publication Name	World Journal of Stem Cells
Manuscript ID	16591
Country	India

Received	2015-01-24 12:42
Peer-Review Started	2015-01-24 13:47
To Make the First Decision	2015-03-06 10:12
Return for Revision	2015-03-15 19:21
Revised	2015-06-27 00:00
Second Decision	2015-07-15 17:26
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2015-08-21 16:22
Articles in Press	2015-08-21 16:22
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2015-09-11 10:11
Publish the Manuscript Online	2015-09-25 17:30

ISSN	1948-0210 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright	© The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Oncology
Manuscript Type	Editorial
Article Title	Emerging role of microRNAs in cancer stem cells: Implications in cancer therapy
Manuscript Source	Invited Manuscript
All Author List	Minal Garg
Funding Agency and Grant Number
Corresponding Author	Minal Garg, Msc, PhD, Assistant Professor, Department of Biochemistry, University of Lucknow, University Road, Lucknow 226007, India. minal14@yahoo.com
Key Words	Cancer stem cells; Drug resistance; Tumor recurrence; MicroRNAs; Cancer therapy
Core Tip	Cancer stem cells (CSCs) which are believed to be the prerequisite for metastasis and tumor recurrence, are endowed with ability to undergo symmetric cell division, capacity for self-renewability, long term proliferation and resistance to anti-neoplasic therapeutic drugs. Regulatory characteristics of microRNAs (miRNAs) which are the clusters of non-coding RNA molecules, include widespread changes in gene expression through gene silencing at post-transcriptional level and are dysregulated in human cancer. Over the past two decades, miRNAs have gained widespread attention due to their involvement in acquisition of stem cell-like properties, regulation and reprogramming by cancer cells during cancer progression. Many studies are coming up which document miRNAs as novel therapeutic tool in targeting CSCs functions, sensitizing them to apoptotic effects of anti-cancer drugs, and reducing tumor burden with no relapse in current clinical settings.
Publish Date	2015-09-25 17:30
Citation	Garg M. Emerging role of microRNAs in cancer stem cells: Implications in cancer therapy. World J Stem Cells 2015; 7(8): 1078-1089
URL	http://www.wjgnet.com/1948-0210/full/v7/i8/1078.htm
DOI	http://dx.doi.org/10.4252/wjsc.v7.i8.1078

Full Article (PDF)	WJSC-7-1078.pdf
Full Article (Word)	WJSC-7-1078.doc
Manuscript File	16591-Review.docx
Answering Reviewers	16591-Answering reviewers.pdf
Audio Core Tip	16591-Audio core tip.mp3
Conflict-of-Interest Disclosure Form	16591-Conflict-of-interest statement.pdf
Copyright License Agreement	16591-Copyright assignment.pdf
Peer-review Report	16591-Peer-review(s).pdf
Journal Editor-in-Chief Review Report	16591-Journal editor-in-chief review report.pdf
Scientific Misconduct Check	16591-Scientific misconduct check.pdf
Scientific Editor Work List	16591-Scientific editor work list.pdf