Publication Name	World Journal of Virology
Manuscript ID	16669
Country	Italy

Received	2015-01-28 11:24
Peer-Review Started	2015-02-05 08:57
To Make the First Decision	2015-04-27 15:33
Return for Revision	2015-04-29 20:52
Revised	2015-06-23 19:09
Second Decision	2015-07-24 11:32
Accepted by Journal Editor-in-Chief	2015-07-26 23:53
Accepted by Executive Editor-in-Chief	2015-08-03 15:44
Articles in Press	2015-08-03 15:44
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2015-08-09 14:13
Publish the Manuscript Online	2015-08-13 10:30

ISSN	2220-3249 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright	© The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
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Website	http://www.wjgnet.com

Category	Virology
Manuscript Type	Editorial
Article Title	Novel antigen delivery systems
Manuscript Source	Invited Manuscript
All Author List	Maria Trovato and Piergiuseppe De Berardinis
Funding Agency and Grant Number	Funding Agency Grant Number NIH R01AI AI074379 MIUR-PON 01_00117
Corresponding Author	Piergiuseppe De Berardinis, PhD, Institute of Protein Biochemistry, National Research Council, Via Pietro Castellino 111, 80131 Naples, Italy. p.deberardinis@ibp.cnr.it
Key Words	Vaccines; Antigen display; Delivery systems; E2 scaffold; Immune response
Core Tip	Several promising strategies of vaccination have been proposed over the past years to treat and/or prevent infectious and cancer diseases. These include live attenuated or inactivated viral vaccines, recombinant viral vectors, DNA vaccines, subunit vaccines, nanoparticle carriers, and lipid-based delivery systems such as liposomes and virosomes. Although some of these suffer from certain limitations (e.g., safety concerns, weak immunogenicity, adverse side-effects associated with adjuvants), recent advances in vaccine technology have provided further insights for guiding vaccine design. Here, we review the current status of antigen delivery systems with emphasis on a versatile and immunogenic vaccine delivery candidate: the “E2 scaffold”.
Publish Date	2015-08-13 10:30
Citation	Trovato M, De Berardinis P. Novel antigen delivery systems. World J Virol 2015; 4(3): 156-168
URL	http://www.wjgnet.com/2220-3249/full/v4/i3/156.htm
DOI	http://dx.doi.org/10.5501/wjv.v4.i3.156

Full Article (PDF)	WJV-4-156.pdf
Full Article (Word)	WJV-4-156.doc
Manuscript File	16669-Review.docx
Answering Reviewers	16669-Answering reviewers.pdf
Audio Core Tip	16669-Audio core tip.mp3
Conflict-of-Interest Disclosure Form	16669-Conflict-of-interest statement.pdf
Copyright License Agreement	16669-Copyright assignment.pdf
Peer-review Report	16669-Peer-review(s).pdf
Journal Editor-in-Chief Review Report	16669-Journal editor-in-chief review report.pdf
Scientific Misconduct Check	16669-Scientific misconduct check.pdf
Scientific Editor Work List	16669-Scientific editor work list.pdf