Publication Name	World Journal of Gastroenterology
Manuscript ID	16730
Country	Türkiye

Received	2015-01-28 08:47
Peer-Review Started	2015-01-28 17:48
To Make the First Decision	2015-03-10 17:50
Return for Revision	2015-03-12 10:40
Revised	2015-03-23 23:20
Second Decision	2015-04-10 11:53
Accepted by Journal Editor-in-Chief	2015-04-13 02:48
Accepted by Executive Editor-in-Chief	2015-04-28 18:13
Articles in Press	2015-04-28 18:14
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2015-06-02 11:38
Publish the Manuscript Online	2015-06-20 17:38

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright	© The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
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Category	Pathology
Manuscript Type	Editorial
Article Title	Neuropilins and liver
Manuscript Source	Invited Manuscript
All Author List	Gülsüm Özlem Elpek
Funding Agency and Grant Number
Corresponding Author	Gülsüm Özlem Elpek, MD, Professor, Department of Pathology, Medical School, Akdeniz University, Dumlupınar Bulvarı, Antalya 07070, Turkey. elpek@akdeniz.edu.tr
Key Words	Neuropilins; Neuropilin-1; Neuropilin-2; Angiogenesis; Liver fibrosis; Vascular endothelial growth factor; Transforming growth factor β1
Core Tip	The contribution of Neuropilins (NRPs) to tumor angiogenesis has been identified in previous research, which has led to the development of NRP-targeted therapies. Although the number of relevant studies is too small to ascertain the precise role of NRPs in liver, the evidence implies an association with tumor behavior, liver regeneration and the progression of fibrosis. The interplay between NRPs and vascular endothelial growth factor, platelet-derived growth factor and transforming growth factor-β support NRPs as potential targets in the prevention of fibrogenesis in chronic liver diseases. However, further studies are needed to clarify whether NRPs may fill the large gaps in our understanding and ability to treat liver diseases.
Publish Date	2015-06-20 17:38
Citation	Elpek GÖ. Neuropilins and liver. World J Gastroenterol 2015; 21(23): 7065-7073
URL	http://www.wjgnet.com/1007-9327/full/v21/i23/7065.htm
DOI	http://dx.doi.org/10.3748/wjg.v21.i23.7065

Full Article (PDF)	WJG-21-7065.pdf
Full Article (Word)	WJG-21-7065.doc
Manuscript File	16730-Review.docx
Answering Reviewers	16730-Answering reviewers.pdf
Audio Core Tip	16730-Audio core tip.mpeg
Conflict-of-Interest Disclosure Form	16730-Conflict-of-interest statement.pdf
Copyright License Agreement	16730-Copyright assignment.pdf
Non-Native Speakers of English Editing Certificate	16730-Language certificate.pdf
Peer-review Report	16730-Peer-review(s).pdf
Scientific Misconduct Check	16730-Scientific misconduct check.pdf
Scientific Editor Work List	16730-Scientific editor work list.pdf