Publication Name	World Journal of Biological Chemistry
Manuscript ID	16754
Country	South Korea

Received	2015-01-29 09:53
Peer-Review Started	2015-02-01 20:01
To Make the First Decision	2015-03-06 10:10
Return for Revision	2015-03-15 18:35
Revised	2015-03-17 00:00
Second Decision	2015-04-10 18:05
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2015-04-20 15:02
Articles in Press	2015-04-20 15:02
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2015-05-04 08:40
Publish the Manuscript Online	2015-05-21 13:33

ISSN	1949-8454 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
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Category	Cardiac & Cardiovascular Systems
Manuscript Type	Editorial
Article Title	MicroRNAs as mediators of cardiovascular disease: Targets to be manipulated
Manuscript Source	Invited Manuscript
All Author List	Seahyoung Lee, Eunhyun Choi, Sung-Man Kim and Ki-Chul Hwang
Funding Agency and Grant Number	Funding Agency Grant Number Korea Science and Engineering Foundation NRF-2011-0019243 Korea Science and Engineering Foundation NRF-2011-0019254 Korea Health 21 RD Project, Ministry of Health and Welfare, Republic of Korea A120478
Corresponding Author	Ki-Chul Hwang, PhD, Distinguished Professor, Director of the Institute for Bio-Medical Convergence, College of Medicine, Catholic Kwandong University, 24 Beomil-ro 579beon-gil, Gangneung, Gangwon-do 210-701, South Korea. kchwang@cku.ac.kr
Key Words	Cardiovascular diseases; MicroRNA; Heart; Endothelial cells; Smooth muscle cells
Core Tip	Accumulating evidence indicates that microRNAs (miRNAs) play important roles in the development and progression of cardiovascular diseases. To date, observational studies such as miRNA-profiling in diseased animals and/or patients have provided valuable information regarding their roles in cardiovascular diseases. For example, dysregulated miRNAs under pathologic conditions have been identified, and their possible targets, whose down-regulation may have contributed to the development of corresponding disease, have been examined. Nevertheless, future studies should be more focused on identifying key mechanisms of miRNA dysregulation during pathogenesis of the cardiovascular system so that optimized counter-measures to prevent/manage cardiovascular disease can be designed and developed.
Publish Date	2015-05-21 13:33
Citation	Lee S, Choi E, Kim SM, Hwang KC. MicroRNAs as mediators of cardiovascular disease: Targets to be manipulated. World J Biol Chem 2015; 6(2): 34-38
URL	http://www.wjgnet.com/1949-8454/full/v6/i2/34.htm
DOI	http://dx.doi.org/10.4331/wjbc.v6.i2.34

Full Article (PDF)	WJBC-6-34.pdf
Full Article (Word)	WJBC-6-34.doc
Manuscript File	16754-Review.docx
Answering Reviewers	16754-Answering reviewers.pdf
Audio Core Tip	16754-Audio core tip.wav
Conflict-of-Interest Disclosure Form	16754-Conflict-of-interest statement.pdf
Copyright License Agreement	16754-Copyright assignment.pdf
Peer-review Report	16754-Peer-review(s).pdf
Scientific Misconduct Check	16754-Scientific misconduct check.pdf
Scientific Editor Work List	16754-Scientific editor work list.pdf