Publication Name	World Journal of Transplantation
Manuscript ID	16805
Country	United States

Received	2015-01-29 21:07
Peer-Review Started	2015-01-30 19:22
First Decision by Editorial Office Director
Return for Revision	2015-05-18 19:58
Revised	2015-06-13 23:11
Publication Fee Transferred
Second Decision by Editor	2015-07-02 09:33
Second Decision by Editor-in-Chief	2015-07-04 03:05
Final Decision by Editorial Office Director	2015-07-14 09:37
Articles in Press	2015-07-14 09:37
Edit the Manuscript by Language Editor
Typeset the Manuscript	2015-09-11 15:38
Publish the Manuscript Online	2015-09-24 18:44

ISSN	2220-3230 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright	© The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
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Website	http://www.wjgnet.com

Category	Transplantation
Manuscript Type	Editorial
Article Title	Minimization vs tailoring: Where do we stand with personalized immunosuppression during renal transplantation in 2015?
Manuscript Source	Invited Manuscript
All Author List	Lajos Zsom, László Wagner and Tibor Fülöp
Funding Agency and Grant Number
Corresponding Author	Tibor Fülöp, MD, Division of Nephrology, Department of Medicine, University of Mississippi Medical Center, 2500 North State Street, L 504, Jackson, MS 39216-4505, United States. tiborfulop.nephro@gmail.com
Key Words	Glucocorticoids; Donor-specific antibodies; Kidney transplantation; Mechanistic (mammalian) target of rapamycin inhibitor; Mycophenolate mofetil; Non-adherence; Calcineurin inhibitor; Sirolimus
Core Tip	When managing individual transplant recipients, awareness of potential treatment-induced complications and pre-existing comorbidities may take precedence over excessively rigid adherence to pre-existing pathways. Potential areas of improvement are: (1) a thorough assessment of immunological and metabolic risk profile of each donor recipient; (2) screening for predictors of graft loss and early signs of antibody-mediated rejection with donor-specific antibodies, protocol biopsies and proteinuria (including close follow up of adverse effects with dose adjustments or conversions as necessary); and (3) increased awareness of the possible link between poor tolerance of a given drug at a given dose and non-adherence with the prescribed regimen.
Publish Date	2015-09-24 18:44
Citation	Zsom L, Wagner L, Fülöp T. Minimization vs tailoring: Where do we stand with personalized immunosuppression during renal transplantation in 2015? World J Transplant 2015; 5(3): 73-80
URL	http://www.wjgnet.com/2220-3230/full/v5/i3/73.htm
DOI	http://dx.doi.org/10.5500/wjt.v5.i3.73

Full Article (PDF)	WJT-5-73.pdf
Full Article (Word)	WJT-5-73.doc
Manuscript File	16805-Review.docx
Answering Reviewers	16805-Answering reviewers.pdf
Audio Core Tip	16805-Audio core tip.mp3
Conflict-of-Interest Disclosure Form	16805-Conflict-of-interest statement.pdf
Copyright License Agreement	16805-Copyright assignment.pdf
Peer-review Report	16805-Peer-review(s).pdf
Journal Editor-in-Chief Review Report	16805-Journal editor-in-chief review report.pdf
Scientific Misconduct Check	16805-Scientific misconduct check.pdf
Scientific Editor Work List	16805-Scientific editor work list.pdf