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9/24/2015 6:44:00 PM | Browse: 459 | Download: 566
Publication Name World Journal of Transplantation
Manuscript ID 16805
Country/Territory United States
Received
2015-01-29 21:07
Peer-Review Started
2015-01-30 19:22
To Make the First Decision
2015-05-14 16:43
Return for Revision
2015-05-18 19:58
Revised
2015-06-13 23:11
Second Decision
2015-07-02 09:33
Accepted by Journal Editor-in-Chief
2015-07-04 03:05
Accepted by Company Editor-in-Chief
2015-07-14 09:37
Articles in Press
2015-07-14 09:37
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2015-09-11 15:38
Publish the Manuscript Online
2015-09-24 18:44
ISSN 2220-3230 (online)
Open Access This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Transplantation
Manuscript Type Editorial
Article Title Minimization vs tailoring: Where do we stand with personalized immunosuppression during renal transplantation in 2015?
Manuscript Source Invited Manuscript
All Author List Lajos Zsom, László Wagner and Tibor Fülöp
Funding Agency and Grant Number
Corresponding author Tibor Fülöp, MD, Division of Nephrology, Department of Medicine, University of Mississippi Medical Center, 2500 North State Street, L 504, Jackson, MS 39216-4505, United States. tiborfulop.nephro@gmail.com
Keywords Glucocorticoids; Donor-specific antibodies; Kidney transplantation; Mechanistic (mammalian) target of rapamycin inhibitor; Mycophenolate mofetil; Non-adherence; Calcineurin inhibitor; Sirolimus
Core Tip When managing individual transplant recipients, awareness of potential treatment-induced complications and pre-existing comorbidities may take precedence over excessively rigid adherence to pre-existing pathways. Potential areas of improvement are: (1) a thorough assessment of immunological and metabolic risk profile of each donor recipient; (2) screening for predictors of graft loss and early signs of antibody-mediated rejection with donor-specific antibodies, protocol biopsies and proteinuria (including close follow up of adverse effects with dose adjustments or conversions as necessary); and (3) increased awareness of the possible link between poor tolerance of a given drug at a given dose and non-adherence with the prescribed regimen.
Publish Date 2015-09-24 18:44
Citation Zsom L, Wagner L, Fülöp T. Minimization vs tailoring: Where do we stand with personalized immunosuppression during renal transplantation in 2015? World J Transplant 2015; 5(3): 73-80
Url http://www.wjgnet.com/2220-3230/full/v5/i3/73.htm
DOI http://dx.doi.org/10.5500/wjt.v5.i3.73
Full Article (PDF) WJT-5-73.pdf
Full Article (Word) WJT-5-73.doc
Manuscript File 16805-Review.docx
Answering Reviewers 16805-Answering reviewers.pdf
Audio Core Tip 16805-Audio core tip.mp3
Conflict-of-Interest Disclosure Form 16805-Conflict-of-interest statement.pdf
Copyright License Agreement 16805-Copyright assignment.pdf
Peer-review Report 16805-Peer-review(s).pdf
Journal Editor-in-Chief Review Report 16805-Journal editor-in-chief review report.pdf
Scientific Misconduct Check 16805-Scientific misconduct check.pdf
Scientific Editor Work List 16805-Scientific editor work list.pdf