Publication Name	World Journal of Gastroenterology
Manuscript ID	17416
Country	Italy

Received	2015-03-06 08:49
Peer-Review Started	2015-03-07 15:56
To Make the First Decision	2015-04-24 19:20
Return for Revision	2015-04-29 16:45
Revised	2015-05-13 04:53
Second Decision	2015-07-17 17:00
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2015-07-18 11:11
Articles in Press	2015-07-18 11:11
Publication Fee Transferred
Edit the Manuscript by Language Editor	2015-09-01 03:39
Typeset the Manuscript	2015-09-23 08:21
Publish the Manuscript Online	2015-09-28 18:06

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access	Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright	© The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
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Website	http://www.wjgnet.com

Category	Oncology
Manuscript Type	Observational Study
Article Title	Intensified intensity-modulated radiotherapy in anal cancer with prevalent HPV p16 positivity
Manuscript Source	Unsolicited Manuscript
All Author List	Liliana Belgioia, Stefano Vagge, Dario Agnese, Stefania Garelli, Roberto Murialdo, Giuseppe Fornarini, Silvana Chiara, Fabio Gallo, Almalina Bacigalupo and Renzo Corvò
Funding Agency and Grant Number
Corresponding Author	Liliana Belgioia, MD, University Research, Department of Radiation Oncology, AOU IRCCS San Martino - IST National Cancer Research Institute and University, 16132 Genoa, Italy. liliana.belgioia@unige.it
Key Words	Anal canal cancer; Intensity-modulated radiotherapy; Simultaneous integrated boost; Helical tomotherapy; HPV
Core Tip	This study evaluated intensity-modulated radiotherapy with simultaneous integrated boost in anal canal cancer of prevalent Human papilloma virus (HPV)-positive patients. The results show excellent outcomes in HPV-positive tumors, and suggest that an intensified radiotherapy schedule associated with chemotherapy is safe and allows the obtaining of oncologic results comparable to the standard schedule without an increase in acute toxicity.
Publish Date	2015-09-28 18:06
Citation	Belgioia L, Vagge S, Agnese D, Garelli S, Murialdo R, Fornarini G, Chiara S, Gallo F, Bacigalupo A, Corvò R. Intensified intensity-modulated radiotherapy in anal cancer with prevalent HPV p16 positivity. World J Gastroenterol 2015; 21(37): 10688-10696
URL	http://www.wjgnet.com/1007-9327/full/v21/i37/10688.htm
DOI	http://dx.doi.org/10.3748/wjg.v21.i37.10688

Full Article (PDF)	WJG-21-10688.pdf
Full Article (Word)	WJG-21-10688.doc
Manuscript File	17416-Review.docx
Answering Reviewers	17416-Answering reviewers.pdf
Audio Core Tip	17416-Audio core tip.mp3
Biostatistics Review Certificate	17416-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form	17416-Conflict-of-interest statement.pdf
Copyright License Agreement	17416-Copyright assignment.pdf
Institutional Review Board Approval Form or Document	17416-Institutional review board statement.pdf
Non-Native Speakers of English Editing Certificate	17416-Language certificate.pdf
Peer-review Report	17416-Peer-review(s).pdf
Scientific Misconduct Check	17416-Scientific misconduct check.pdf
Scientific Editor Work List	17416-Scientific editor work list.pdf