Publication Name	World Journal of Gastroenterology
Manuscript ID	17508
Country	Japan

Received	2015-03-10 18:09
Peer-Review Started	2015-03-11 10:07
To Make the First Decision	2015-04-13 14:40
Return for Revision	2015-04-15 18:54
Revised	2015-04-16 18:00
Second Decision	2015-06-03 08:32
Accepted by Journal Editor-in-Chief	2015-06-03 17:11
Accepted by Company Editor-in-Chief	2015-06-10 17:40
Articles in Press	2015-06-10 17:40
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2015-07-06 14:31
Publish the Manuscript Online	2015-09-28 11:42

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
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Category	Gastroenterology & Hepatology
Manuscript Type	Letter to the Editor
Article Title	Corticosteroid and nucleoside analogue for hepatitis B virus-related acute liver failure
Manuscript Source	Unsolicited Manuscript
All Author List	Keiichi Fujiwara, Shin Yasui and Osamu Yokosuka
Funding Agency and Grant Number
Corresponding Author	Keiichi Fujiwara, MD, PhD, Department of Gastroenterology and Nephrology, Graduate School of Medicine, Chiba University, 1-8-1 Inohana, Chuo-ku, Chiba 260-8670, Chiba, Japan. fujiwara-cib@umin.ac.jp
Key Words	Chronic hepatitis B; Exacerbation; Acute liver failure; Nucleoside analogue; Corticosteroid
Core Tip	Nucleoside analogues generally need some weeks before hepatitis B virus DNA becomes unde-tectable and therefore they may be too slow to influence the clinical course of acute severe liver failure, and the overwhelming anti-viral immune response might actively contribute to the effectiveness of treatment. We have performed prospective study of early introduction of high-dose corticosteroid with/without nucleoside analogue for severe acute reactivation of chronic hepatitis B since 1997, and recovery rate without liver transplantation improved from 25% to 70%.
Publish Date	2015-09-28 11:42
Citation	Fujiwara K, Yasui S, Yokosuka O. Corticosteroid and nucleoside analogue for hepatitis B virus-related acute liver failure. World J Gastroenterol 2015; 21(36): 10485-10486
URL	http://www.wjgnet.com/1007-9327/full/v21/i36/10485.htm
DOI	http://dx.doi.org/10.3748/wjg.v21.i36.10485

Full Article (PDF)	WJG-21-10485.pdf
Full Article (Word)	WJG-21-10485.doc
Manuscript File	17508-Review.docx
Answering Reviewers	17508-Answering reviewers.pdf
Audio Core Tip	17508-Audio core tip.mp3
Conflict-of-Interest Disclosure Form	17508-Conflict-of-interest statement.pdf
Copyright License Agreement	17508-Copyright assignment.pdf
Peer-review Report	17508-Peer-review(s).pdf
Journal Editor-in-Chief Review Report	17508-Journal editor-in-chief review report.pdf
Scientific Misconduct Check	17508-Scientific misconduct check.pdf
Scientific Editor Work List	17508-Scientific editor work list.pdf