| ISSN |
2220-3206 (online) |
| Open Access |
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Psychiatry |
| Manuscript Type |
Retrospective Study |
| Article Title |
Risk for emerging bipolar disorder, variants, and symptoms in children with attention deficit hyperactivity disorder, now grown up
|
| Manuscript Source |
Invited Manuscript |
| All Author List |
Ahmed Z Elmaadawi, Peter S Jensen, L Eugene Arnold, Brooke SG Molina, Lily Hechtman, Howard B Abikoff, Stephen P Hinshaw, Jeffrey H Newcorn, Laurence Lee Greenhill, James M Swanson and Cathryn A Galanter |
| Funding Agency and Grant Number |
|
| Corresponding Author |
Dr. Ahmed Z Elmaadawi, Assistant Professor, Department of Psychiatry, Indiana University School of Medicine, 707 N. Michigan Street, Suite 400, South Bend, IN 46601, United States. aelmaada@iupui.edu |
| Key Words |
Multimodal treatment study of attention deficit hyperactivity disorder; Irritability; Attention deficit hyperactivity disorder; Diagnostic interview schedule for children; Bipolar disorder |
| Core Tip |
Despite its formal DSM delineation, alternative pediatric bipolar disorder (BD) definitions have been debated for decades. Some research suggests that attention deficit hyperactivity disorder (ADHD) poses a risk for BD and that pediatric BD presents differently as non-episodic, greater chronicity, and more frequent irritability. In our study, we found the ADHD status is not a risk factor for developing BD over 14 years of follow-ups. When we controlled for overlapping ADHD/BD, nonspecific symptoms showed decreasing rates of BD in ADHD-diagnosed children. Clinicians are encouraged to pay greater attention to specific symptoms of mania in order to establish an accurate BD diagnosis. Furthermore, irritability (DSM criteria A2), was a nonspecific symptom of mania and linked to common psychopathologies in the early development of these children. |
| Publish Date |
2015-12-18 19:53 |
| Citation |
Elmaadawi AZ, Jensen PS, Arnold LE, Molina BSG, Hechtman L, Abikoff HB, Hinshaw SP, Newcorn JH, Greenhill LL, Swanson JM, Galanter CA. Risk for emerging bipolar disorder, variants, and symptoms in children with attention deficit hyperactivity disorder, now grown up. World J Psychiatr 2015; 5(4): 412-424 |
| URL |
http://www.wjgnet.com/2220-3206/full/v5/i4/412.htm |
| DOI |
http://dx.doi.org/10.5498/wjp.v5.i4.412 |
