Publication Name	World Journal of Gastroenterology
Manuscript ID	18280
Country	United States

Received	2015-04-14 14:47
Peer-Review Started	2015-04-16 12:45
To Make the First Decision	2015-05-18 13:00
Return for Revision	2015-05-20 09:12
Revised	2015-06-09 10:10
Second Decision	2015-06-10 09:21
Accepted by Journal Editor-in-Chief	2015-06-10 12:20
Accepted by Executive Editor-in-Chief	2015-06-16 11:49
Articles in Press	2015-06-16 11:49
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2015-07-16 16:09
Publish the Manuscript Online	2015-08-08 15:26

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright	© The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
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Category	Gastroenterology & Hepatology
Manuscript Type	Review
Article Title	Microscopic colitis: A review of etiology, treatment and refractory disease
Manuscript Source	Invited Manuscript
All Author List	Tina Park, David Cave and Christopher Marshall
Funding Agency and Grant Number
Corresponding Author	Christopher Marshall, MD, Assistant Professor, Department of Medicine, Division of Gastroenterology, University of Massachusetts, 55 Lake Avenue North, Worcester, MA 01655, United States. christopher.marshall@umassmemorial.org
Key Words	Chronic diarrhea; Etiology of microscopic colitis; Collagenous colitis; Refractory microscopic colitis; Microscopic colitis; Lymphocytic colitis; Steroid-dependent microscopic colitis
Core Tip	The etiology of microscopic colitis (MC) is unknown. There is a strong association with autoimmune disorders, smoking, and medications, such as non-steroidal anti-inflammatory drugs, proton pump inhibitors, and selective serotonin reuptake inhibitors. There are no societal guidelines on how to manage patients with MC. Data is strongest for the use of budesonide. Budesonide can rapidly induce clinical remission but relapse occurs frequently after discontinuation of budesonide. Anti-diarrheals may be used alone in mild MC or in conjunction with other therapies in moderate to severe MC. There is limited data on management of steroid-dependent or refractory MC but anti-TNF and diverting ileostomy may be options.
Publish Date	2015-08-08 15:26
Citation	Park T, Cave D, Marshall C. Microscopic colitis: A review of etiology, treatment and refractory disease. World J Gastroenterol 2015; 21(29): 8804-8810
URL	http://www.wjgnet.com/1007-9327/full/v21/i29/8804.htm
DOI	http://dx.doi.org/10.3748/wjg.v21.i29.8804

Full Article (PDF)	WJG-21-8804.pdf
Full Article (Word)	WJG-21-8804.doc
Manuscript File	18280-Review.docx
Answering Reviewers	18280-Answering reviewers.pdf
Audio Core Tip	18280-Audio core tip.mp3
Conflict-of-Interest Disclosure Form	18280-Conflict-of-interest statement.pdf
Copyright License Agreement	18280-Copyright assignment.pdf
Peer-review Report	18280-Peer-review(s).pdf
Journal Editor-in-Chief Review Report	18280-Journal editor-in-chief review report.pdf
Scientific Misconduct Check	18280-Scientific misconduct check.pdf
Scientific Editor Work List	18280-Scientific editor work list.pdf