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10/23/2015 3:58:00 PM | Browse: 518 | Download: 757
Publication Name World Journal of Gastroenterology
Manuscript ID 18455
Country/Territory United States
Received
2015-04-21 08:47
Peer-Review Started
2015-04-21 19:49
To Make the First Decision
2015-05-18 12:21
Return for Revision
2015-05-22 11:09
Revised
2015-06-16 07:12
Second Decision
2015-07-27 20:19
Accepted by Journal Editor-in-Chief
2015-07-28 04:18
Accepted by Company Editor-in-Chief
2015-08-25 18:47
Articles in Press
2015-08-25 18:47
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2015-08-31 16:49
Publish the Manuscript Online
2015-10-23 15:45
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology and Hepatology
Manuscript Type Topic Highlights
Article Title Genetic epidemiology of irritable bowel syndrome
Manuscript Source Invited Manuscript
All Author List Jasbir Makker, Sridhar Chilimuri and Jonathan N Bella
Funding Agency and Grant Number
Corresponding author Jonathan N Bella, MD, Department of Medicine, Bronx-Lebanon Hospital Center and Albert Einstein College of Medicine, 12th Floor, 1650 Grand Concourse, Bronx, NY 10457, United States. jonnbella@earthlink.net
Keywords Irritable bowel syndrome; Single-nucleotide polymorphism; Serotonin; Familial aggregation; Genetics
Core Tip Irritable bowel syndrome (IBS) is believed to result from interplay of several factors including hypersensitivity of the bowel, altered bowel motility, inflammation and stress. Familial aggregation of cases and twin studies underscore the genetic basis of IBS. Different researchers have studied several candidate genes but the evidence so far linking IBS to specific genes is inconsistent and weak. Genome wide association studies that can examine several common genetic variants are needed to design newer drugs and diagnostic methods.
Publish Date 2015-10-23 15:45
Citation Makker J, Chilimuri S, Bella JN. Genetic epidemiology of irritable bowel syndrome. World J Gastroenterol 2015; 21(40): 11353-11361
Url http://www.wjgnet.com/1007-9327/full/v21/i40/11353.htm
DOI http://dx.doi.org/10.3748/wjg.v21.i40.11353
Full Article (PDF) WJG-21-11353.pdf
Full Article (Word) WJG-21-11353.doc
Manuscript File 18455-Review.docx
Answering Reviewers 18455-Answering reviewers.pdf
Audio Core Tip 18455-Audio core tip.m4a
Conflict-of-Interest Disclosure Form 18455-Conflict-of-interest statement.pdf
Copyright License Agreement 18455-Copyright assignment.pdf
Peer-review Report 18455-Peer-review(s).pdf
Journal Editor-in-Chief Review Report 18455-Journal editor-in-chief review report.pdf
Scientific Misconduct Check 18455-Scientific misconduct check.pdf
Scientific Editor Work List 18455-Scientific editor work list.pdf