Publication Name	World Journal of Gastroenterology
Manuscript ID	18712
Country	Germany

Received	2015-04-27 10:47
Peer-Review Started	2015-04-29 15:02
To Make the First Decision	2015-08-26 09:48
Return for Revision	2015-08-31 15:39
Revised	2015-09-29 02:08
Second Decision	2015-11-03 09:23
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2015-11-13 15:57
Articles in Press	2015-11-13 15:57
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2015-11-29 20:41
Publish the Manuscript Online	2016-01-20 16:55

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
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Category	Transplantation
Manuscript Type	Topic Highlights
Article Title	Hemostasis in liver transplantation: Pathophysiology, monitoring, and treatment
Manuscript Source	Invited Manuscript
All Author List	Matthias Hartmann, Cynthia Szalai and Fuat H Saner
Funding Agency and Grant Number
Corresponding Author	Matthias Hartmann, Professor, Klinik für Anästhesiologie und Intensivmedizin, Universitätsklinikum Essen, Hufelandstr. 55, D-45122 Essen, Germany. matthias.hartmann@uni-due.de
Key Words	Liver transplantation; Hemostasis; Bed-side monitoring; Thrombelastography; Thrombelastometry; Coagulation factors
Core Tip	Hemostasis in patients presenting for liver transplantation is often characterized by a reduction in both pro- and anticoagulant factors. During surgery, the rebalanced hemostasis system can be stressed by bleeding, hemodynamic shock, tissue damage or substitution of blood products with resultant diffuse bleeding or thrombus formation. Thrombelastography/thrombelastometry can guide substitution of blood products and reduces bleeding, transfusion of blood products, and eventual mortality. It is, however, important to state that bed-side methods are not capable of detecting alterations in anticoagulant pathways. Thus cautious coagulation management is recommended to avoid potential devastating thrombotic complications.
Publish Date	2016-01-20 16:55
Citation	Hartmann M, Szalai C, Saner FH. Hemostasis in liver transplantation: Pathophysiology, monitoring, and treatment. World J Gastroenterol 2016; 22(4): 1541-1550
URL	http://www.wjgnet.com/1007-9327/full/v22/i4/1541.htm
DOI	http://dx.doi.org/10.3748/wjg.v22.i4.1541

Full Article (PDF)	WJG-22-1541.pdf
Full Article (Word)	WJG-22-1541.doc
Manuscript File	18712-Review.docx
Answering Reviewers	18712-Answering reviewers.pdf
Audio Core Tip	18712-Audio core tip.mp3
Conflict-of-Interest Disclosure Form	18712-Conflict-of-interest statement.pdf
Copyright License Agreement	18712-Copyright assignment.pdf
Non-Native Speakers of English Editing Certificate	18712-Language certificate.pdf
Peer-review Report	18712-Peer-review(s).pdf
Scientific Misconduct Check	18712-Scientific misconduct check.pdf
Scientific Editor Work List	18712-Scientific editor work list.pdf