Publication Name	World Journal of Gastroenterology
Manuscript ID	19234
Country	Italy

Received	2015-04-30 19:30
Peer-Review Started	2015-05-08 11:23
To Make the First Decision	2015-07-14 11:42
Return for Revision	2015-07-14 20:47
Revised	2015-08-14 20:46
Second Decision	2015-10-23 16:42
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2015-11-09 16:55
Articles in Press	2015-11-09 16:55
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2015-12-01 17:19
Publish the Manuscript Online	2015-12-31 13:27

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access	Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright	© The Author(s) 2016. Published by Baishideng Publishing Group Inc. All rights reserved.
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Category	Gastroenterology & Hepatology
Manuscript Type	Topic Highlights
Article Title	Prediction of hepatocellular carcinoma biological behavior in patient selection for liver transplantation
Manuscript Source	Invited Manuscript
All Author List	Umberto Cillo, Tommaso Giuliani, Marina Polacco, Luz Maria Herrero Manley, Gino Crivellari and Alessandro Vitale
Funding Agency and Grant Number
Corresponding Author	Umberto Cillo, MD, FEBS, Hepatobiliary Surgery and Liver Transplantation Unit, Department of General Surgery and Organ Transplantation, University Hospital of Padua, Via 8 Febbraio, 35128 Padova, Italy. cillo@unipd.it
Key Words	Hepatocellular carcinoma; Liver Alpha-fetoprotein; Transplantation; Biomarkers; Histopathology; Recurrence; Integrated prognostic tool
Core Tip	An integrated model predicting post-transplant survival of hepatocellular carcinoma patients after liver transplantation has not yet been defined. Current selection criteria for liver transplantation that do not consider its biological aggressiveness are mainly based on morphological tumor markers that offer only a static view of the tumor. Many biomarkers predicting post-transplant outcome and stratifying those patients who are candidates for liver transplantation are under evaluation. An integrated prognostic model will make it possible to quantify the tumor burden via functional imaging modalities as well as biological markers.
Publish Date	2015-12-31 13:27
Citation	Cillo U, Giuliani T, Polacco M, Herrero Manley LM, Crivellari G, Vitale A. Prediction of hepatocellular carcinoma biological behavior in patient selection for liver transplantation. World J Gastroenterol 2016; 22(1): 232-252
URL	http://www.wjgnet.com/1007-9327/full/v22/i1/232.htm
DOI	http://dx.doi.org/10.3748/wjg.v22.i1.232

Full Article (PDF)	WJG-22-232.pdf
Full Article (Word)	WJG-22-232.doc
Manuscript File	19234-Review.docx
Answering Reviewers	19234-Answering reviewers.pdf
Audio Core Tip	19234-Audio core tip.wav
Conflict-of-Interest Disclosure Form	19234-Conflict-of-interest statement.pdf
Copyright License Agreement	19234-Copyright assignment.pdf
Non-Native Speakers of English Editing Certificate	19234-Language certificate.pdf
Peer-review Report	19234-Peer-review(s).pdf
Scientific Misconduct Check	19234-Scientific misconduct check.pdf
Scientific Editor Work List	19234-Scientific editor work list.pdf