Publication Name	World Journal of Diabetes
Manuscript ID	19395
Country	India

Received	2015-05-07 09:31
Peer-Review Started	2015-05-08 13:40
First Decision by Editorial Office Director
Return for Revision	2015-07-10 11:54
Revised	2015-07-25 17:13
Publication Fee Transferred
Second Decision by Editor	2015-09-02 15:36
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director	2015-09-08 15:57
Articles in Press	2015-09-08 15:57
Edit the Manuscript by Language Editor
Typeset the Manuscript	2015-09-25 21:24
Publish the Manuscript Online	2015-10-13 15:31

ISSN	1948-9358 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright	© The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
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Category	Neurosciences
Manuscript Type	Review
Article Title	Molecular and biochemical trajectories from diabetes to Alzheimer’s disease: A critical appraisal
Manuscript Source	Invited Manuscript
All Author List	Rajat Sandhir and Smriti Gupta
Funding Agency and Grant Number
Corresponding Author	Rajat Sandhir, Professor, Department of Biochemistry, Panjab University, Sector 14, Chandigarh 160014, India. sandhir@pu.ac.in
Key Words	Diabetes mellitus; Alzheimer’s disease; Insulin; Type 2 diabetes; Type 3 diabetes
Core Tip	This review provides a synopsis in which a metabolic disturbance becomes indispensible for life and emerges as a molecular signal defect leading to a syndrome with multiple complications. Insulin is a spotlight player which draws a trajectory from diabetes to Alzheimer’s disease with multiple divergence and convergence. We have discussed their interplay to speculate their shared molecular footprints. These biochemical and molecular commonalities provide a clue to the investigators to look inside a therapy with a common experimental and clinical platform and also provide an insight for new interventions as future perspective to find a potential stone to kill two birds together.
Publish Date	2015-10-13 15:31
Citation	Sandhir R, Gupta S. Molecular and biochemical trajectories from diabetes to Alzheimer’s disease: A critical appraisal. World J Diabetes 2015; 6(12): 1223-1242
URL	http://www.wjgnet.com/1948-9358/full/v6/i12/1223.htm
DOI	http://dx.doi.org/10.4239/wjd.v6.i12.1223

Full Article (PDF)	WJD-6-1223.pdf
Full Article (Word)	WJD-6-1223.doc
Manuscript File	19395-Review.docx
Answering Reviewers	19395-Answering reviewers.pdf
Audio Core Tip	19395-Audio core tip.wav
Conflict-of-Interest Disclosure Form	19395-Conflict-of-interest statement.pdf
Copyright License Agreement	19395-Copyright assignment.pdf
Peer-review Report	19395-Peer-review(s).pdf
Scientific Misconduct Check	19395-Scientific misconduct check.pdf
Scientific Editor Work List	19395-Scientific editor work list.pdf