Publication Name	World Journal of Nephrology
Manuscript ID	19484
Country	Italy

Received	2015-05-10 15:16
Peer-Review Started	2015-05-12 16:34
First Decision by Editorial Office Director
Return for Revision	2015-06-09 12:13
Revised
Publication Fee Transferred
Second Decision by Editor	2015-11-30 09:36
Second Decision by Editor-in-Chief	2015-11-30 16:08
Final Decision by Editorial Office Director	2015-12-11 16:08
Articles in Press	2015-12-11 16:08
Edit the Manuscript by Language Editor
Typeset the Manuscript	2015-12-28 15:47
Publish the Manuscript Online	2016-01-06 20:46

ISSN	2220-6124 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
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Category	Urology & Nephrology
Manuscript Type	Minireviews
Article Title	Secondary amyloidosis in autoinflammatory diseases and the role of inflammation in renal damage
Manuscript Source	Invited Manuscript
All Author List	Roberto Scarpioni, Marco Ricardi and Vittorio Albertazzi
Funding Agency and Grant Number
Corresponding Author	Roberto Scarpioni, MD, Department of Nephrology and Dialysis, AUSL Hospital “Guglielmo da Saliceto”, via Taverna 49, 29121 Piacenza, Italy. rscarpioni@hotmail.com
Key Words	Inflammation; Autoinflammatory disease; Chronic kidney disease; Interleukin-1; Dialysis; Caspase; Proteinuria; Amyloidosis; Nod-like receptor protein-3
Core Tip	Inflammation may also negatively produce elevation of proinflammatory cytokines. Recently, attention was addressed to the formation of the intracellular inflammasome nod-like receptor protein-3 (NLRP-3) activating caspase-1, the enzyme required for the maturation of interleukin-1. IL1, in turn, regulate serum amyloid A, a major acute-phase with also proinflammatory properties. An interesting new scenario on the pathogenesis of renal diseases (namely ANCA-associated glomerulonephritis vasculitis, urate-crystal nephropathy, contrast nephropathy, acute kidney injury, reactive systemic amyloidosis) and reactive systemic amyloidosis was opened, and NLRP3 inflammasome was recently identified as a possible therapeutic target in the treatment of chronic kidney disease.
Publish Date	2016-01-06 20:46
Citation	Scarpioni R, Ricardi M, Albertazzi V. Secondary amyloidosis in autoinflammatory diseases and the role of inflammation in renal damage. World J Nephrol 2016; 5(1): 66-75
URL	http://www.wjgnet.com/2220-6124/full/v5/i1/66.htm
DOI	http://dx.doi.org/10.5527/wjn.v5.i1.66

Full Article (PDF)	WJN-5-66.pdf
Full Article (Word)	WJN-5-66.doc
Manuscript File	19484-Review.docx
Answering Reviewers	19484-Answering reviewers.pdf
Audio Core Tip	19484-Audio core tip.m4a
Conflict-of-Interest Disclosure Form	19484-Conflict-of-interest statement.pdf
Copyright License Agreement	19484-Copyright assignment.pdf
Peer-review Report	19484-Peer-review(s).pdf
Journal Editor-in-Chief Review Report	19484-Journal editor-in-chief review report.pdf
Scientific Misconduct Check	19484-Scientific misconduct check.pdf
Scientific Editor Work List	19484-Scientific editor work list.pdf