BPG is committed to discovery and dissemination of knowledge
Articles Published Processes
10/23/2015 3:58:00 PM | Browse: 1390 | Download: 1929
 |
Received |
|
2015-05-11 16:34 |
|
Peer-Review Started |
|
2015-05-14 14:28 |
|
To Make the First Decision |
|
2015-06-02 14:54 |
|
Return for Revision |
|
2015-06-06 18:30 |
|
Revised |
|
2015-06-26 20:50 |
|
Second Decision |
|
2015-09-28 16:10 |
 |
Accepted by Journal Editor-in-Chief |
|
|
|
Accepted by Executive Editor-in-Chief |
|
2015-09-30 10:20 |
|
Articles in Press |
|
2015-09-30 10:20 |
|
Publication Fee Transferred |
|
|
|
Edit the Manuscript by Language Editor |
|
|
|
Typeset the Manuscript |
|
2015-10-13 17:13 |
|
Publish the Manuscript Online |
|
2015-10-23 15:45 |
| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
|
| Copyright |
© The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
|
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
|
| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
|
| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Review |
| Article Title |
Tight junction disruption: Helicobacter pylori and dysregulation of the gastric mucosal barrier
|
| Manuscript Source |
Invited Manuscript |
| All Author List |
Tyler J Caron, Kathleen E Scott, James G Fox and Susan J Hagen |
| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| Department of Surgery funds, BIDMC and NIH |
P30 DK034854 (SJH) |
| Department of Surgery funds, BIDMC and NIH |
R01 CA093405 |
| Department of Surgery funds, BIDMC and NIH |
P30 ES002109 |
| Department of Surgery funds, BIDMC and NIH |
R01 OD011141 |
| Department of Surgery funds, BIDMC and NIH |
No. P01 CA028842 (JGF) |
| NIH |
T32 OD0109978 (JGF, to Dr. Caron and Dr. Scott) |
|
| Corresponding Author |
Susan J Hagen, PhD, Department of Surgery, Beth Israel Deaconess Medical Center, E/RW-871, 330 Brookline Avenue, Boston, MA 01125, United States. shagen@bidmc.harvard.edu
|
| Key Words |
Helicobacter pylori; Tight junction; Claudins; Paracellular permeability; Stomach; Cytotoxin-associated gene A; Vacuolating cytotoxin; Lipopolysaccharide; Urease; Ammonia |
| Core Tip |
Tight junction dysfunction is a risk factor for cancer development during Helicobacter pylori (H. pylori) infection. The recent identification of numerous barrier-forming claudins has greatly improved our understanding of properties that regulate selective permeation across the tight junction in general, but little is known about the role of claudins in the stomach, or in H. pylori infection. In this article, we review the current state of knowledge on stomach tight junction composition and organization, discuss the details of claudin expression in various species and in cultured gastric cells, and discuss the implications of tight junction dysregulation in gastric cancer pathogenesis.
|
| Publish Date |
2015-10-23 15:45 |
| Citation |
Caron TJ, Scott KE, Fox JG, Hagen SJ. Tight junction disruption: Helicobacter pylori and dysregulation of the gastric mucosal barrier. World J Gastroenterol 2015; 21(40): 11411-11427 |
| URL |
http://www.wjgnet.com/1007-9327/full/v21/i40/11411.htm |
| DOI |
http://dx.doi.org/10.3748/wjg.v21.i40.11411 |
© 2004-2025 Baishideng Publishing Group Inc. All rights reserved. 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
California Corporate Number: 3537345
