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Articles Published Processes
12/24/2015 9:30:00 PM | Browse: 963 | Download: 1861
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Received |
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2015-05-15 17:47 |
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Peer-Review Started |
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2015-05-20 09:42 |
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To Make the First Decision |
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2015-07-26 17:31 |
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Return for Revision |
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2015-08-03 14:49 |
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Revised |
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2015-08-13 03:08 |
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Second Decision |
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2015-10-10 19:33 |
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Accepted by Journal Editor-in-Chief |
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2015-10-11 20:22 |
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Accepted by Executive Editor-in-Chief |
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2015-10-19 15:10 |
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Articles in Press |
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2015-10-19 15:10 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2015-12-09 11:45 |
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Publish the Manuscript Online |
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2015-12-24 21:31 |
| ISSN |
2308-3840 (online) |
| Open Access |
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Statistics & Probability |
| Manuscript Type |
Evidence-Based Medicine |
| Article Title |
Towards better meta-analyses in assisted reproductive technology: Fixed, random or multivariate models?
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Philippe Lehert |
| Funding Agency and Grant Number |
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| Corresponding Author |
Dr. Philippe Lehert, PhD, Professor of Statistics, Faculty of Medicine, the University of Melbourne, 801/250 St Kilda Rd, Southbank 3006, Victoria, Australia. philippe.lehert@gmail.com |
| Key Words |
Meta-analysis; Random model; Fixed model; Assisted reproductive techniques; In vitro fertilization |
| Core Tip |
The numerous meta-analyses (MA) published in assisted reproduction technology (ART) are often characterized by conflicting results. This paper provides evidence that the choice of the meta-analytical model constitutes a major concern. We first identified a general profile of characteristics of the ART studies, compare different models by simulation and resolve a practical case. MA based on the fixed model produce severe biases and falsely significant differences. Better results derive from the random model. For partially reported multiple endpoints, the multivariate model takes advantage of the between-endpoint inter-correlation and provides consistent estimates, better precision, and higher power. |
| Publish Date |
2015-12-24 21:31 |
| Citation |
Lehert P. Towards better meta-analyses in assisted reproductive technology: Fixed, random or multivariate models? World J Meta-Anal 2015; 3(6): 225-231 |
| URL |
http://www.wjgnet.com/2308-3840/full/v3/i6/225.htm |
| DOI |
http://dx.doi.org/10.13105/wjma.v3.i6.225 |
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