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Articles Published Processes
10/14/2015 12:06:00 PM | Browse: 1137 | Download: 1611
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Received |
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2015-05-18 15:04 |
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Peer-Review Started |
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2015-05-20 08:15 |
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To Make the First Decision |
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2015-06-23 15:14 |
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Return for Revision |
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2015-06-27 16:44 |
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Revised |
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2015-07-06 23:30 |
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Second Decision |
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2015-09-12 22:04 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2015-09-14 11:34 |
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Articles in Press |
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2015-09-14 11:34 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2015-09-22 10:16 |
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Publish the Manuscript Online |
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2015-10-14 12:06 |
| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Topic Highlights |
| Article Title |
Immune and non-immune responses to hepatitis C virus infection
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Jiaren Sun, Ricardo Rajsbaum and MinKyung Yi |
| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| NIH |
AI109100 (to Sun J) |
| NIH |
R01AI110358 (to Yi M) |
| UTMB Institute for Human Infection and Immunity and UT System Rising STAR Award |
to Rajsbaum R |
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| Corresponding Author |
Jiaren Sun, MD, PhD, Department of Microbiology and Immunology, Institute for Human Infections and Immunity, University of Texas Medical Branch, 301 University Blvd, Galveston, TX 77555-1070, United States. jisun@utmb.edu |
| Key Words |
Hepatitis C virus; Hepatitis; T cell; Direct-acting antiviral; Innate immune response |
| Core Tip |
Hepatitis C virus (HCV) is an etiologic agent that can cause severe liver diseases, including chronic hepatitis, liver fibrosis, liver cirrhosis, and hepatocellular carcinoma. Although newly available direct-acting antivirals (DAAs) are very effective in viral clearance in patients, it remains unclear as to how many of the world’s infected individuals will benefit from the new DAAs. In this review, we focus on recent studies that address the host responses critical for viral clearance and disease resolution. Additional discussion is devoted to the prophylactic vaccine development and innate responses against HCV infection. Current theories on how the ubiquitin system and interferon-stimulated genes may affect HCV replication are also discussed. |
| Publish Date |
2015-10-14 12:06 |
| Citation |
un J, Rajsbaum R, Yi M. Immune and non-immune responses to hepatitis C virus infection. World J Gastroenterol 2015; 21(38): 10739-10748 |
| URL |
http://www.wjgnet.com/1007-9327/full/v21/i38/10739.htm |
| DOI |
http://dx.doi.org/10.3748/wjg.v21.i38.10739 |
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