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10/14/2015 12:06:00 PM | Browse: 489 | Download: 697
Publication Name World Journal of Gastroenterology
Manuscript ID 19717
Country/Territory United States
2015-05-18 15:04
Peer-Review Started
2015-05-20 08:15
To Make the First Decision
2015-06-23 15:14
Return for Revision
2015-06-27 16:44
2015-07-06 23:30
Second Decision
2015-09-12 22:04
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2015-09-14 11:34
Articles in Press
2015-09-14 11:34
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2015-09-22 10:16
Publish the Manuscript Online
2015-10-14 12:06
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology and Hepatology
Manuscript Type Topic Highlights
Article Title Immune and non-immune responses to hepatitis C virus infection
Manuscript Source Invited Manuscript
All Author List Jiaren Sun, Ricardo Rajsbaum and MinKyung Yi
Funding Agency and Grant Number
Funding Agency Grant Number
NIH AI109100 (to Sun J)
NIH R01AI110358 (to Yi M)
UTMB Institute for Human Infection and Immunity and UT System Rising STAR Award to Rajsbaum R
Corresponding author Jiaren Sun, MD, PhD, Department of Microbiology and Immunology, Institute for Human Infections and Immunity, University of Texas Medical Branch, 301 University Blvd, Galveston, TX 77555-1070, United States. jisun@utmb.edu
Keywords Hepatitis C virus; Hepatitis; T cell; Direct-acting antiviral; Innate immune response
Core Tip Hepatitis C virus (HCV) is an etiologic agent that can cause severe liver diseases, including chronic hepatitis, liver fibrosis, liver cirrhosis, and hepatocellular carcinoma. Although newly available direct-acting antivirals (DAAs) are very effective in viral clearance in patients, it remains unclear as to how many of the world’s infected individuals will benefit from the new DAAs. In this review, we focus on recent studies that address the host responses critical for viral clearance and disease resolution. Additional discussion is devoted to the prophylactic vaccine development and innate responses against HCV infection. Current theories on how the ubiquitin system and interferon-stimulated genes may affect HCV replication are also discussed.
Publish Date 2015-10-14 12:06
Citation un J, Rajsbaum R, Yi M. Immune and non-immune responses to hepatitis C virus infection. World J Gastroenterol 2015; 21(38): 10739-10748
Url http://www.wjgnet.com/1007-9327/full/v21/i38/10739.htm
DOI http://dx.doi.org/10.3748/wjg.v21.i38.10739
Full Article (PDF) WJG-21-10739.pdf
Full Article (Word) WJG-21-10739.doc
Manuscript File 19717-Review.docx
Answering Reviewers 19717-Answering reviewers.pdf
Audio Core Tip 19717-Audio core tip.mp3
Conflict-of-Interest Disclosure Form 19717-Conflict-of-interest statement.pdf
Copyright License Agreement 19717-Copyright assignment.pdf
Peer-review Report 19717-Peer-review(s).pdf
Scientific Misconduct Check 19717-Scientific misconduct check.pdf
Scientific Editor Work List 19717-Scientific editor work list.pdf