Publication Name	World Journal of Orthopedics
Manuscript ID	19866
Country	United States

Received	2015-05-24 12:27
Peer-Review Started	2015-05-25 21:09
To Make the First Decision	2015-08-16 17:23
Return for Revision	2015-08-22 18:19
Revised	2015-09-15 08:20
Second Decision	2015-11-12 14:00
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2015-11-25 15:36
Articles in Press	2015-11-25 15:36
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2016-01-08 19:24
Publish the Manuscript Online	2016-01-15 09:08

ISSN	2218-5836 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
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Category	Orthopedics
Manuscript Type	Minireviews
Article Title	Role of negative pressure wound therapy in total hip and knee arthroplasty
Manuscript Source	Invited Manuscript
All Author List	Marcelo BP Siqueira, Deepak Ramanathan, Alison K Klika, Carlos A Higuera and Wael K Barsoum
Funding Agency and Grant Number
Corresponding Author	Alison K Klika, MS, Research Program Manager, Department of Orthopaedic Surgery, Orthopaedic and Rheumatologic Institute, Cleveland Clinic Foundation, 9500 Euclid Avenue, Cleveland, OH 44195, United States. klikaa@ccf.org
Key Words	Negative-pressure wound therapy; Vacuum-assisted closure; Total knee replacement; Total hip replacement; Prosthesis-related infections
Core Tip	The application of negative pressure wound therapy (NPWT) in arthroplasty has generated much interest. Its proposed mechanisms of action include macrodeformation and microdeformation of the wound bed, fluid removal, and stabilization of the wound environment. There is little evidence to support the use of NPWT as an adjunctive treatment for surgical wound drainage. However, there appears to be strong clinical evidence for the prophylactic use of NPWT after arthroplasty in patients that are at high risk for postoperative wound drainage. Several clinical trials involving single-use NPWT devices for this purpose are currently in progress.
Publish Date	2016-01-15 09:08
Citation	Siqueira MBP, Ramanathan D, Klika AK, Higuera CA, Barsoum WK. Role of negative pressure wound therapy in total hip and knee arthroplasty. World J Orthop 2016; 7(1): 30-37
URL	http://www.wjgnet.com/2218-5836/full/v7/i1/30.htm
DOI	http://dx.doi.org/10.5312/wjo.v7.i1.30

Full Article (PDF)	WJO-7-30.pdf
Full Article (Word)	WJO-7-30.doc
Manuscript File	19866-Review.docx
Answering Reviewers	19866-Answering reviewers.pdf
Audio Core Tip	19866-Audio core tip.mp3
Conflict-of-Interest Disclosure Form	19866-Conflict-of-interest statement.pdf
Copyright License Agreement	19866-Copyright assignment.pdf
Peer-review Report	19866-Peer-review(s).pdf
Scientific Misconduct Check	19866-Scientific misconduct check.pdf
Scientific Editor Work List	19866-Scientific editor work list.pdf