Publication Name	World Journal of Gastrointestinal Pharmacology and Therapeutics
Manuscript ID	20039
Country	Italy

Received	2015-05-28 09:40
Peer-Review Started	2015-05-30 15:26
To Make the First Decision	2015-08-14 15:27
Return for Revision	2015-08-22 15:47
Revised	2015-08-28 18:00
Second Decision	2015-10-21 17:31
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2015-11-04 17:35
Articles in Press	2015-11-04 17:35
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2016-01-18 16:37
Publish the Manuscript Online	2016-01-29 11:06

ISSN	2150-5349 (online)
Open Access	Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright	© The Author(s) 2016. Published by Baishideng Publishing Group Inc. All rights reserved.
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Website	http://www.wjgnet.com

Category	Gastroenterology & Hepatology
Manuscript Type	Editorial
Article Title	Proton pump inhibitor prescription abuse and sepsis in cirrhosis
Manuscript Source	Invited Manuscript
All Author List	Antonio Picardi and Umberto Vespasiani-Gentilucci
Funding Agency and Grant Number
Corresponding Author	Antonio Picardi, MD, PhD, Internal Medicine and Hepatology Unit, University Campus Bio-Medico, Via Alvaro del Portillo 200, 00128 Rome, Italy. a.picardi@unicampus.it
Key Words	Proton pump inhibitors; Liver cirrhosis; Bacterial infection; Sepsis
Core Tip	Many prescriptions of proton pump inhibitors (PPIs) are made without adhering to standard recognized indications. PPIs are ordinarily well tolerated but are not free of side-effects, and, in patients with liver cirrhosis, concerns are accruing on a possible role for PPIs in increasing the risk of infections and sepsis. As evidences of different power are accumulating, prospective studies are needed. However, prescribers should put definitely more attention in adhering to the recognized indications for the use of PPIs, especially in patients with cirrhosis. Otherwise, doctors could be responsible for “abuse” of prescription.
Publish Date	2016-01-29 11:06
Citation	Picardi A, Vespasiani-Gentilucci U. Proton pump inhibitor prescription abuse and sepsis in cirrhosis. World J Gastrointest Pharmacol Ther 2016; 7(1): 1-4
URL	http://www.wjgnet.com/2150-5349/full/v7/i1/1.htm
DOI	http://dx.doi.org/10.4292/wjgpt.v7.i1.1

Full Article (PDF)	WJGPT-7-1.pdf
Full Article (Word)	WJGPT-7-1.doc
Manuscript File	20039-Review.docx
Answering Reviewers	20039-Answering reviewers.pdf
Audio Core Tip	20039-Audio core tip.wma
Conflict-of-Interest Disclosure Form	20039-Conflict-of-interest statement.pdf
Copyright License Agreement	20039-Copyright assignment.pdf
Peer-review Report	20039-Peer-review(s).pdf
Scientific Misconduct Check	20039-Scientific misconduct check.pdf
Scientific Editor Work List	20039-Scientific editor work list.pdf