| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
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| Copyright |
© The Author(s) 2016. Published by Baishideng Publishing Group Inc. All rights reserved.
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| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Oncology |
| Manuscript Type |
Retrospective Study |
| Article Title |
Prognostic value of perioperative leukocyte count in resectable gastric cancer
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Xiao-Feng Chen, Jing Qian, Dong Pei, Chen Zhou, Oluf Dimitri Røe, Fang Zhu, Shao-Hua He, Ying-Ying Qian, Yue Zhou, Jun Xu, Jin Xu, Xiao Li, Guo-Qiang Ping, Yi-Qian Liu, Ping Wang, Ren-Hua Guo and Yong-Qian Shu |
| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| National Natural Science Foundation of China |
81301896 |
| Natural Science Foundation of the Colleges and Universities in Jiangsu Province of China |
13KJB320011 |
| Program for Development of Innovative Research Teams, Jiangsu Province Clinical Science and Technology Projects (Clinical Research Center) |
BL 2012008 |
| Priority Academic Program Development of Jiangsu Higher Education Institutions |
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| Provincial Initiative Program for Excellency Disciplines of Jiangsu Province of China. |
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| Corresponding Author |
Yong-Qian Shu, Professor, Head, Department of Oncology, The First Affiliated Hospital of Nanjing Medical University, No. 300 Guangzhou Road, Nanjing 210029, Jiangsu Province, China. yq_shu@163.com
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| Key Words |
Gastric cancer; Leukocytosis; Leukopenia; Postoperative; Prognosis |
| Core Tip |
It has been noted that a subset of gastric cancer patients who underwent gastrectomy with normal baseline white blood cell counts experience mild to moderate leukopenia after surgery. This retrospective analysis investigated preoperative and postoperative leukocyte counts in gastric cancer patients to assess their relationship with clinicopathologic characteristics and their potential prognostic value. The results show, for the first time, that preoperative leukocytosis and postoperative leukopenia significantly correlated with overall survival in resectable gastric cancer treated with adjuvant chemotherapy. This suggests the prognostic importance of perioperative total leukocyte count for operable gastric cancer.
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| Publish Date |
2016-03-02 13:35 |
| Citation |
Chen XF, Qian J, Pei D, Zhou C, Røe OD, Zhu F, He SH, Qian YY, Zhou Y, Xu J, Xu J, Li X, Ping GQ, Liu YQ, Wang P, Guo RH, Shu YQ. Prognostic value of perioperative leukocyte count in resectable gastric cancer. World J Gastroenterol 2016; 22(9): 2818-2827 |
| URL |
http://www.wjgnet.com/1007-9327/full/v22/i9/2818.htm |
| DOI |
http://dx.doi.org/10.3748/wjg.v22.i9.2818 |
