Publication Name	World Journal of Clinical Infectious Diseases
Manuscript ID	20415
Country	France

Received	2015-06-04 09:28
Peer-Review Started	2015-06-08 17:22
To Make the First Decision	2015-07-28 10:45
Return for Revision	2015-08-10 08:32
Revised	2015-09-12 00:00
Second Decision	2015-09-29 17:20
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2015-10-13 18:04
Articles in Press	2015-10-13 18:04
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2015-11-17 16:50
Publish the Manuscript Online	2015-11-27 16:31

ISSN	2220-3176 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright	© The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
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Category	Infectious Diseases
Manuscript Type	Editorial
Article Title	How could we reduce antifungal use in the intensive care unit?
Manuscript Source	Invited Manuscript
All Author List	Anahita Rouzé, Karim Jaffal and Saad Nseir
Funding Agency and Grant Number
Corresponding Author	Saad Nseir, Professor, Critical Care Center, R. Salengro Hospital, University Hospital of Lille, boulevard du Pr Leclercq, 59037 Lille cedex, France. s-nseir@chru-lille.fr
Key Words	Antifungals; Biomarkers; Colonization; Infection; Preemptive treatment
Core Tip	Prompt appropriate antifungal treatment is associated with better outcome in patients with confirmed infections, this treatment has several drawbacks. Reducing antifungal treatment in the intensive care unit (ICU) is feasible, and would allow avoiding drawbacks of this treatment without negative impact on outcome. Antifungal stewardship, preemptive antifungal treatment, based on colonization index and fungal biomarkers; and de-escalation of antifungal treatment based on microbiology results and fungal biomarkers could be suggested to reduce antifungal use in the ICU, and are currently under investigation.
Publish Date	2015-11-27 16:31
Citation	Rouzé A, Jaffal K, Nseir S. How could we reduce antifungal use in the intensive care unit? World J Clin Infect Dis 2015; 5(4): 55-58
URL	http://www.wjgnet.com/2220-3176/full/v5/i4/55.htm
DOI	http://dx.doi.org/10.5495/wjcid.v5.i4.55

Full Article (PDF)	WJCID-5-55.pdf
Full Article (Word)	WJCID-5-55.doc
Manuscript File	20415-Review.docx
Answering Reviewers	20415-Answering reviewers.pdf
Audio Core Tip	20415-Audio core tip.mp3
Conflict-of-Interest Disclosure Form	20415-Conflict-of-interest statement.pdf
Copyright License Agreement	20415-Copyright assignment.pdf
Peer-review Report	20415-Peer-review(s).pdf
Scientific Misconduct Check	20415-Scientific misconduct check.pdf
Scientific Editor Work List	20415-Scientific editor work list.pdf