Publication Name	World Journal of Critical Care Medicine
Manuscript ID	20573
Country	United States

Received	2015-06-11 08:49
Peer-Review Started	2015-06-11 22:14
To Make the First Decision	2015-08-16 14:44
Return for Revision	2015-08-25 16:30
Revised	2015-10-15 00:00
Second Decision	2015-12-18 11:27
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2016-01-04 16:18
Articles in Press	2016-01-04 16:18
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2016-01-15 08:31
Publish the Manuscript Online

ISSN	2220-3141(online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright	© The Author(s) 2016. Published by Baishideng Publishing Group Inc. All rights reserved.
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Website	http://www.wjgnet.com

Category	Respiratory System
Manuscript Type	Minireviews
Article Title	Preemptive mechanical ventilation can block progressive acute lung injury
Manuscript Source	Invited Manuscript
All Author List	Benjamin Sadowitz, Sumeet Jain, Michaela Kollisch-Singule, Joshua Satalin, Penny Andrews, Nader Habashi, Louis A Gatto and Gary Nieman
Funding Agency and Grant Number
Corresponding Author	Joshua Satalin, Lab Manager (Cardio¬pulmonary Critical Care Lab), Department of Surgery, Upstate Medical University, 750 East Adams Street, Syracuse, NY 13210, United States. satalinj@upstate.edu
Key Words	Mechanical ventilation; Acute lung injury; Acute respiratory distress syndrome; Airway pressure release ventilation
Core Tip	Mortality from acute respiratory distress syndrome (ARDS) remains unacceptably high. Treating fulminant ARDS, however, is currently relegated to supportive care measures only. Thus, the best treatment for ARDS may lie with preventive measures. Indeed, since ARDS is a progressive disease, treating this disease in its subclinical phases may prevent the disease from ever occurring. In this regard, early protective mechanical ventilation with airway pressure release ventilation appears to offer substantial benefit and may be the prophylactic treatment of choice for preventing ARDS.
Publish Date
Citation	Sadowitz B, Jain S, Kollisch-Singule M, Satalin J, Andrews P, Habashi N, Gatto LA, Nieman G. Preemptive mechanical ventilation can block progressive acute lung injury. World J Crit Care Med 2016; 5(1): 74-82
URL	http://www.wjgnet.com/2220-3141/full/v5/i1/74.htm
DOI	http://dx.doi.org/10.5492/wjccm.v5.i1.74

Full Article (PDF)	WJCCM-5-74.pdf
Full Article (Word)	WJCCM-5-74.doc
Manuscript File	20573-Review.docx
Answering Reviewers	20573-Answering reviewers.pdf
Audio Core Tip	20573-Audio core tip.mp3
Conflict-of-Interest Disclosure Form	20573-Conflict-of-interest statement.pdf
Copyright License Agreement	20573-Copyright assignment.PDF
Peer-review Report	20573-Peer-review(s).pdf
Scientific Misconduct Check	20573-Scientific misconduct check.pdf
Scientific Editor Work List	20573-Scientific editor work list.pdf