Publication Name	World Journal of Gastrointestinal Oncology
Manuscript ID	21041
Country	United States

Received	2015-06-28 17:32
Peer-Review Started	2015-07-11 09:13
To Make the First Decision	2015-07-28 10:52
Return for Revision	2015-08-04 12:06
Revised	2015-08-17 06:56
Second Decision	2015-09-10 08:29
Accepted by Journal Editor-in-Chief	2015-09-11 05:05
Accepted by Executive Editor-in-Chief	2015-09-18 13:34
Articles in Press	2015-09-18 13:34
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2015-10-26 17:47
Publish the Manuscript Online	2015-11-17 08:51

ISSN	1948-5204 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright	© The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
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Category	Oncology
Manuscript Type	Minireviews
Article Title	Immunotherapeutic approaches in biliary tract carcinoma: Current status and emerging strategies
Manuscript Source	Invited Manuscript
All Author List	Eric I Marks and Nelson S Yee
Funding Agency and Grant Number
Corresponding Author	Nelson S Yee, MD, PhD, Division of Hematology-Oncology, Program of Experimental Therapeutics, Department of Medicine, Penn State Hershey Medical Center, Penn State Hershey Cancer Institute, 500 University Drive, Hershey, PA 17033-0850, United States. nyee@hmc.psu.edu
Key Words	Adoptive immunotherapy; Cancer vaccines; Biliary tract carcinoma; Cholangiocarcinoma; Gallbladder carcinoma; Immunotherapy; Precision treatment
Core Tip	Advances in cancer immunology have led to development of novel therapeutics that focuses on enhancing the immune system against biliary tract cancer. These include peptide- or dendritic cell-based vaccines, adoptive immunotherapy, and immunostimulatory cytokines. Immunotherapy is generally well tolerated with good potential for developing into treatment. The efficacy of immunotherapy may be improved by reversal of tumor-associated immunosuppression and through discovery of novel antigen targets. Integration of targeted immunotherapeutics with molecular profiling of biliary tumor is expected to make a positive impact on advancing towards the goal of developing precision treatment of patients with this highly lethal disease.
Publish Date	2015-11-17 08:51
Citation	Marks EI, Yee NS. Immunotherapeutic approaches in biliary tract carcinoma: Current status and emerging strategies. World J Gastrointest Oncol 2015; 7(11): 338-346
URL	http://www.wjgnet.com/1948-5204/full/v7/i11/338.htm
DOI	http://dx.doi.org/10.4251/wjgo.v7.i11.338

Full Article (PDF)	WJGO-7-338.pdf
Full Article (Word)	WJGO-7-338.doc
Manuscript File	21041-Review.docx
Answering Reviewers	21041-Answering reviewers.pdf
Audio Core Tip	21041-Audio core tip.mp3
Conflict-of-Interest Disclosure Form	21041-Conflict-of-interest statement.pdf
Copyright License Agreement	21041-Copyright assignment.pdf
Peer-review Report	21041-Peer-review(s).pdf
Journal Editor-in-Chief Review Report	21041-Journal editor-in-chief review report.pdf
Scientific Misconduct Check	21041-Scientific misconduct check.pdf
Scientific Editor Work List	21041-Scientific editor work list.pdf