Publication Name	World Journal of Gastrointestinal Pharmacology and Therapeutics
Manuscript ID	21136
Country	United States

Received	2015-06-29 14:54
Peer-Review Started	2015-07-02 19:35
To Make the First Decision	2015-09-11 15:03
Return for Revision	2015-09-17 15:33
Revised	2015-11-09 00:56
Second Decision	2015-12-07 09:10
Accepted by Journal Editor-in-Chief	2015-12-08 06:13
Accepted by Company Editor-in-Chief	2015-12-18 16:51
Articles in Press	2015-12-18 16:51
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2016-04-14 21:55
Publish the Manuscript Online	2016-04-20 23:11

ISSN	2150-5349 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright	© The Author(s) 2016. Published by Baishideng Publishing Group Inc. All rights reserved.
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Category	Gastroenterology & Hepatology
Manuscript Type	Systematic Reviews
Article Title	Review of efficacy and safety of laxatives use in geriatrics
Manuscript Source	Unsolicited Manuscript
All Author List	Manhal Izzy, Anju Malieckal, Erin Little and Sury Anand
Funding Agency and Grant Number
Corresponding Author	Manhal Izzy, MD, Division of Gastro­enterology and Liver Diseases, Montefiore Medical Center, Albert Einstein College of Medicine, 111 East 210th Street, Bronx, NY 10467, United States. mizzy@montefiore.org
Key Words	Chronic constipation; Laxatives; Elderly; Lubiprostone; Linaclotide; Prucalopride
Core Tip	Laxatives are among the most commonly prescribed medications for elderly patients, however, data about safety and efficacy of laxatives in this patient population are limited. We show in this paper, based on reviewing geriatric studies, that senna combinations and polyethylene glycol appear to have better outcomes in this population than other classic laxatives. We also discuss here the promising results of the new agents, lubiprostone, linaclotide, and prucalopride, which can be helpful in treating geriatric populations in the near future.
Publish Date	2016-04-20 23:11
Citation	Izzy M, Malieckal A, Little E, Anand S. Review of efficacy and safety of laxatives use in geriatrics. World J Gastrointest Pharmacol Ther 2016; 7(2): 334-342
URL	http://www.wjgnet.com/2150-5349/full/v7/i2/334.htm
DOI	http://dx.doi.org/10.4292/wjgpt.v7.i2.334

Full Article (PDF)	WJGPT-7-334.pdf
Full Article (Word)	WJGPT-7-334.doc
Manuscript File	21136-Review.docx
Answering Reviewers	21136-Answering reviewers.pdf
Audio Core Tip	21136-Audio core tip.mp3
Biostatistics Review Certificate	21136-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form	21136-Conflict-of-interest statement.pdf
Copyright License Agreement	21136-Copyright assignment.pdf
Peer-review Report	21136-Peer-review(s).pdf
Journal Editor-in-Chief Review Report	21136-Journal editor-in-chief review report.pdf
Scientific Misconduct Check	21136-Scientific misconduct check.pdf
Scientific Editor Work List	21136-Scientific editor work list.pdf