Publication Name	World Journal of Gastrointestinal Pharmacology and Therapeutics
Manuscript ID	21345
Country	Japan

Received	2015-07-07 15:51
Peer-Review Started	2015-07-13 17:28
To Make the First Decision	2015-07-27 15:57
Return for Revision	2015-07-31 17:04
Revised	2015-08-28 07:49
Second Decision	2015-10-14 08:47
Accepted by Journal Editor-in-Chief	2015-10-14 12:35
Accepted by Executive Editor-in-Chief	2015-11-17 09:25
Articles in Press	2015-11-17 09:25
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2016-01-19 22:02
Publish the Manuscript Online	2016-01-29 11:06

ISSN	2150-5349 (online)
Open Access	Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright	© The Author(s) 2016. Published by Baishideng Publishing Group Inc. All rights reserved.
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Category	Oncology
Manuscript Type	Minireviews
Article Title	Dendritic cell-based vaccine for pancreatic cancer in Japan
Manuscript Source	Invited Manuscript
All Author List	Masato Okamoto, Masanori Kobayashi, Yoshikazu Yonemitsu, Shigeo Koido and Sadamu Homma
Funding Agency and Grant Number
Corresponding Author	Masato Okamoto, DDS, PhD, Professor, Department of Advanced Immunotherapeutics, Kitasato Uni­versity School of Pharmacy, 5-9-1 Shirokane, Minato-ku, Tokyo 108-8641, Japan. okamotom@pharm.kitasato-u.ac.jp
Key Words	Dendritic cell; Cancer vaccine; Pancreatic cancer; Cancer immunotherapy; Anti-cancer immunity
Core Tip	Dendritic cell (DC)-based cancer vaccine is expected as a strategy to augment the antigen-specific anti-cancer immune response. Vaccell, a DC vaccine which was optimized to fight against a cancer, has been developed in Japan. Here, we reviewed the development and clinical effects of the “Vaccell”. We conducted large-scale retrospective observations as well as prospective clinical trials, and obtained the findings strongly suggesting that there are “Responders” that the clinical benefits are provided by the DC vaccine. We are now planning a pivotal study of the Vaccell in Japan.
Publish Date	2016-01-29 11:06
Citation	Okamoto M, Kobayashi M, Yonemitsu Y, Koido S, Homma S. Dendritic cell-based vaccine for pancreatic cancer in Japan. World J Gastrointest Pharmacol Ther 2016; 7(1): 133-138
URL	http://www.wjgnet.com/2150-5349/full/v7/i1/133.htm
DOI	http://dx.doi.org/10.4292/wjgpt.v7.i1.133

Full Article (PDF)	WJGPT-7-133.pdf
Full Article (Word)	WJGPT-7-133.doc
Manuscript File	21345-Review.docx
Answering Reviewers	21345-Answering reviewers.pdf
Audio Core Tip	21345-Audio core tip.wav
Conflict-of-Interest Disclosure Form	21345-Conflict-of-interest statement.pdf
Copyright License Agreement	21345-Copyright assignment.pdf
Peer-review Report	21345-Peer-review(s).pdf
Journal Editor-in-Chief Review Report	21345-Journal editor-in-chief review report.pdf
Scientific Misconduct Check	21345-Scientific misconduct check.pdf
Scientific Editor Work List	21345-Scientific editor work list.pdf