Publication Name	World Journal of Immunology
Manuscript ID	21378
Country	India

Received	2015-07-09 09:14
Peer-Review Started	2015-07-14 09:11
To Make the First Decision	2015-09-16 09:14
Return for Revision	2015-09-22 17:53
Revised	2015-10-07 11:59
Second Decision	2015-11-09 11:04
Accepted by Journal Editor-in-Chief	2015-11-09 15:33
Accepted by Company Editor-in-Chief	2015-11-25 16:10
Articles in Press	2015-11-25 16:10
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2016-03-24 18:01
Publish the Manuscript Online	2016-03-28 08:57

ISSN	2219-2824 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
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Category	Immunology
Manuscript Type	Review
Article Title	Essential vitamins for an effective T cell response
Manuscript Source	Invited Manuscript
All Author List	Ritobrata Goswami and Mark H Kaplan
Funding Agency and Grant Number
Corresponding Author	Ritobrata Goswami, PhD, Institute of Life Sciences, Ahmedabad University, University Road, Navrangpura, Ahmedabad 380009, Gujarat, India. ritobrata.goswami@ahduni.edu.in
Key Words	Vitamin D; Retinoic acid; T helper cells; Cytokines; Transcription factors; Allergy; Autoimmune diseases
Core Tip	Vitamins are organic compounds that are required in small quantities as nutrients. When used as dietary supplements, vitamins can be used to treat diseases and maintain physiological processes including bone and skin health. Vitamins also play important roles in immune system including lymphocyte activation, and T helper cell differentiation. Among all the vitamins, vitamin A and D have garnered more interest in clinical setting. In this review we have focused on how vitamin A and D regulate adaptive immunity especially how both the vitamins modulate T cell responses. We have highlighted the mechanisms how these vitamins affect T helper cell differentiation. How these vitamins affect inflammatory disorders including allergy and autoimmune diseases have also been described in this review. The purpose of this review is to suggest the potential of dietary supplements such as vitamin A and D can be used to treat inflammatory disorders.
Publish Date	2016-03-28 08:57
Citation	Goswami R, Kaplan MH. Essential vitamins for an effective T cell response. World J Immunol 2016; 6(1): 39-59
URL	http://www.wjgnet.com/2219-2824/full/v6/i1/39.htm
DOI	http://dx.doi.org/10.5411/wji.v6.i1.39

Full Article (PDF)	WJI-6-39.pdf
Full Article (Word)	WJI-6-39.doc
Manuscript File	21378-Review.docx
Answering Reviewers	21378-Answering reviewers.pdf
Audio Core Tip	21378-Audio core tip.mp3
Conflict-of-Interest Disclosure Form	21378-Conflict-of-interest statement.pdf
Copyright License Agreement	21378-Copyright assignment.pdf
Peer-review Report	21378-Peer-review(s) .pdf
Journal Editor-in-Chief Review Report	21378-Journal editor-in-chief review report.pdf
Scientific Misconduct Check	21378-Scientific misconduct check.pdf
Scientific Editor Work List	21378-Scientific editor work list.pdf