Publication Name	World Journal of Obstetrics and Gynecology
Manuscript ID	21500
Country	United States

Received	2015-08-01 08:40
Peer-Review Started	2015-08-06 08:30
To Make the First Decision	2015-09-16 08:58
Return for Revision	2015-09-23 12:23
Revised	2015-10-27 07:52
Second Decision	2015-11-27 11:55
Accepted by Journal Editor-in-Chief	2015-11-27 12:38
Accepted by Executive Editor-in-Chief	2015-12-15 09:12
Articles in Press	2015-12-15 09:12
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2016-01-23 20:32
Publish the Manuscript Online	2016-01-31 19:20

ISSN	2218-6220 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
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Category	Obstetrics & Gynecology
Manuscript Type	Minireviews
Article Title	Amniocentesis: A contemporary review
Manuscript Source	Invited Manuscript
All Author List	Katherine Ann Connolly and Keith Arnold Eddleman
Funding Agency and Grant Number
Corresponding Author	Katherine Ann Connolly, MD, Division of Maternal-Fetal Medicine, Department of Obstetrics, Gyneco­logy and Reproductive Sciences, Mount Sinai Hospital, 5 East 98th Street, Room 256, New York, NY 10029, United States. katherine.connolly@mssm.edu
Key Words	Amniocentesis; Prenatal diagnosis; Invasive genetic testing; Procedure related loss rates; Cell free fetal DNA testing; Fetal lung maturity; Intraamniotic infection
Core Tip	Invasive testing remains the only way to provide comprehensive testing for chromosomal abnor-malities. Despite availability of cell free fetal DNA testing, amniocentesis should still be offered to all women who desire complete genetic testing. Amniocentesis is also useful if intraamniotic infection is suspected, but the clinical picture is unclear. Addi-tionally, when late preterm delivery is indicated, amnio-centesis need not be used. There are, however, some instances when delivery timing is unclear and amniocentesis for fetal lung maturity may provide information to guide delivery timing. Amniocentesis is a relatively safe procedure. We counsel patients that technique has changed since the original studies in the 1970s and feel comfortable quoting a loss rate of 1/500-1/1000 based on contemporary data.
Publish Date	2016-01-31 19:20
Citation	Connolly KA, Eddleman KA. Amniocentesis: A contemporary review. World J Obstet Gynecol 2016; 5(1): 58-65
URL	http://www.wjgnet.com/2218-6220/full/v5/i1/58.htm
DOI	http://dx.doi.org/10.5317/wjog.v5.i1.58

Full Article (PDF)	WJOG-5-58.pdf
Full Article (Word)	WJOG-5-58.doc
Manuscript File	21500-Review.docx
Answering Reviewers	21500-Answering reviewers.pdf
Audio Core Tip	21500-Audio core tip.mp3
Conflict-of-Interest Disclosure Form	21500-Conflict-of-interest statement.pdf
Copyright License Agreement	21500-Copyright assignment.pdf
Peer-review Report	21500-Peer-review(s).pdf
Journal Editor-in-Chief Review Report	21500-Journal editor-in-chief review report.pdf
Scientific Misconduct Check	21500-Scientific misconduct check.pdf
Scientific Editor Work List	21500-Scientific editor work list.pdf