Publication Name	World Journal of Methodology
Manuscript ID	21600
Country	Japan

Received	2015-07-28 17:48
Peer-Review Started	2015-08-06 08:22
To Make the First Decision	2015-09-28 13:35
Return for Revision	2015-10-10 20:41
Revised	2015-10-21 18:03
Second Decision	2015-12-23 16:37
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2016-01-07 16:35
Articles in Press	2016-01-07 16:35
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2016-03-04 15:26
Publish the Manuscript Online	2016-03-18 09:50

ISSN	2222-0682 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright	© The Author(s) 2016. Published by Baishideng Publishing Group Inc. All rights reserved.
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Category	Infectious Diseases
Manuscript Type	Observational Study
Article Title	Efficient management and maintenance of ultrasonic nebulizers to prevent microbial contamination
Manuscript Source	Invited Manuscript
All Author List	Yoko Ida, Hiroaki Ohnishi, Kouji Araki, Ryoichi Saito, Shin Kawai and Takashi Watanabe
Funding Agency and Grant Number
Corresponding Author	Hiroaki Ohnishi, MD, PhD, Department of Laboratory Medicine, Kyorin University School of Medicine, 6-20-2 Shinkawa, Mitaka, Tokyo 181-8611, Japan. onishi@ks.kyorin-u.ac.jp
Key Words	Prevention; Contamination; Burkholderia cepacia; Randomly amplified polymorphic DNA assay; Ultrasonic nebulizer
Core Tip	In this study, we sought the cause of an outbreak of Burkholderia cepacia complex (Bcc) infec-tion among inpatients using ultrasonic nebulizers and evaluated the efficacy of new methods for nebulizer maintenance introduced following the outbreak. Precise investigation revealed damaged diaphragms in many nebulizers, which we speculated would be the major cause of Bcc contamination of nebulizers and subsequent Bcc infection. The new maintenance methods for nebu-lizers, including restriction of the usage period, thorough disinfection, and routine check for diaphragm breakage, remarkably reduced Bcc isolation from nebulizers and patients’ samples.
Publish Date	2016-03-18 09:50
Citation	Ida Y, Ohnishi H, Araki K, Saito R, Kawai S, Watanabe T. Efficient management and maintenance of ultrasonic nebulizers to prevent microbial contamination. World J Methodol 2016; 6(1): 126-132
URL	http://www.wjgnet.com/2222-0682/full/v6/i1/126.htm
DOI	http://dx.doi.org/10.5662/wjm.v6.i1.126

Full Article (PDF)	WJM-6-126.pdf
Full Article (Word)	WJM-6-126.doc
Manuscript File	21600-Review.docx
Answering Reviewers	21600-Answering reviewers.pdf
Audio Core Tip	21600-Audio core tip.mp3
Biostatistics Review Certificate	Biostatistics_Statement_20150728123430.docx
Conflict-of-Interest Disclosure Form	21600-Conflict-of-interest statement.pdf
Copyright License Agreement	21600-Copyright assignment.pdf
Signed Informed Consent Form(s) or Document(s)	Informed_Consent_Statement_20150728123512.docx
Institutional Review Board Approval Form or Document	21600-Institutional review board statement.pdf
Non-Native Speakers of English Editing Certificate	21600-Language certificate.pdf
Peer-review Report	21600-Peer-review(s).pdf
Scientific Misconduct Check	21600-Scientific misconduct check.pdf
Scientific Editor Work List	21600-Scientific editor work list.pdf