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2/22/2016 10:45:00 AM | Browse: 495 | Download: 602
Publication Name World Journal of Cardiology
Manuscript ID 21861
Country/Territory Italy
Received
2015-07-31 08:50
Peer-Review Started
2015-07-31 14:08
To Make the First Decision
2015-09-16 09:00
Return for Revision
2015-09-28 11:47
Revised
2015-09-28 21:19
Second Decision
2015-12-11 12:31
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2015-12-18 17:16
Articles in Press
2015-12-18 17:16
Publication Fee Transferred
Edit the Manuscript by Language Editor
2016-01-02 03:43
Typeset the Manuscript
2016-02-03 09:49
Publish the Manuscript Online
2016-02-22 10:45
ISSN 1949-8462 (online)
Open Access This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2016. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Cardiac and Cardiovascular Systems
Manuscript Type Minireviews
Article Title Novel epigenetic-based therapies useful in cardiovascular medicine
Manuscript Source Invited Manuscript
All Author List Claudio Napoli, Vincenzo Grimaldi, Maria Rosaria De Pascale, Linda Sommese, Teresa Infante and Andrea Soricelli
Funding Agency and Grant Number
Corresponding author Vincenzo Grimaldi, MB, BiolD, Division of Immunohematology, Transfusion Medicine and Transplant Immunology, Department of Internal Medicine and Specialistic Unit, Azienda Ospedaliera Universitaria (AOU), Second University of Naples, Piazza L. Miraglia 2, 80138 Naples, Italy. vincenzo.grimaldi@policliniconapoli.it
Keywords Epigenetics; Cardiovascular diseases; Heart failure; Inhibitors of histone deacetylases; Antisense microRNAs
Core Tip Recent evidence suggests that specific epigenetic regulatory mechanisms play key roles in cardiac differe?ntiation, homeostasis, injury response, and disease development. Drug therapies that work via epigenetic mechanisms are currently limited to antineoplastic agents; large controlled trials are required to establish whether current possible candidate antisense microRNAs or histone deacetylase inhibitors could offer better therapeutic benefits in cardiovascular disease. We review recent findings on the epigenetic control of several cardiovascular diseases and the new challenges for therapeutic strategies in cardiovascular diseases.
Publish Date 2016-02-22 10:45
Citation Napoli C, Grimaldi V, De Pascale MR, Sommese L, Infante T, Soricelli A. Novel epigenetic-based therapies useful in cardiovascular medicine. World J Cardiol 2016; 8(2): 211-219
Url http://www.wjgnet.com/1949-8462/full/v8/i2/211.htm
DOI http://dx.doi.org/10.4330/wjc.v8.i2.211
Full Article (PDF) WJC-8-211.pdf
Full Article (Word) WJC-8-211.doc
Manuscript File 21861-Review.docx
Answering Reviewers 21861-Answering reviewers.pdf
Audio Core Tip 21861-Audio core tip.mp3
Conflict-of-Interest Disclosure Form 21861-Conflict-of-interest statement.pdf
Copyright License Agreement 21861-Copyright assignment.pdf
Non-Native Speakers of English Editing Certificate Editing_Certificate_20150730184908.pdf
Peer-review Report 21861-Peer-review(s).pdf
Scientific Misconduct Check 21861-Scientific misconduct check.pdf
Scientific Editor Work List 21861-Scientific editor work list.pdf