Publication Name	World Journal of Gastroenterology
Manuscript ID	22188
Country	United States

Received	2015-08-19 08:34
Peer-Review Started	2015-08-20 08:21
To Make the First Decision	2015-09-09 16:59
Return for Revision	2015-09-13 12:54
Revised	2015-09-24 02:18
Second Decision	2015-11-25 18:30
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2015-12-08 17:11
Articles in Press	2015-12-08 17:11
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2016-01-22 17:16
Publish the Manuscript Online	2016-03-14 08:44

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright	© The Author(s) 2016. Published by Baishideng Publishing Group Inc. All rights reserved.
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Category	Toxicology
Manuscript Type	Letter to the Editor
Article Title	Liuweiwuling tablets protect against acetaminophen hepatotoxicity: What is the protective mechanism?
Manuscript Source	Unsolicited Manuscript
All Author List	Kuo Du and Hartmut Jaeschke
Funding Agency and Grant Number	Funding Agency Grant Number National Institutes of Health R01 DK102142 National Institutes of Health R01 AA12916 National Institute of General Medical Sciences of the National Institutes of Health 8 P20 GM103549-07
Corresponding Author	Hartmut Jaeschke, PhD, ATS, Department of Pharmacology, Toxicology and Therapeutics, University of Kansas Medical Center, 3901 Rainbow Blvd., MS 1018, Kansas City, KS 66160, United States. hjaeschke@kumc.edu
Key Words	Acetaminophen hepatotoxicity; Liuweiwuling; Sterile inflammation; Natural products; Liver regeneration
Core Tip	The reduced inflammatory response and the increased liver regeneration by Liuweiwuling treatment are more likely secondary effects of the protection by inhibition of metabolic activation of acetaminophen rather than the primary mechanism of protection.
Publish Date	2016-03-14 08:44
Citation	Du K, Jaeschke H. Liuweiwuling tablets protect against acetaminophen hepatotoxicity: What is the protective mechanism? World J Gastroenterol 2016; 22(11): 3302-3304
URL	http://www.wjgnet.com/1007-9327/full/v22/i11/3302.htm
DOI	http://dx.doi.org/10.3748/wjg.v22.i11.3302

Full Article (PDF)	WJG-22-3302.pdf
Full Article (Word)	WJG-22-3302.doc
Manuscript File	22188-Review.docx
Answering Reviewers	22188-Answering reviewers.pdf
Audio Core Tip	22188-Audio core tip.mp3
Conflict-of-Interest Disclosure Form	22188-Conflict-of-Interest Statement.pdf
Copyright License Agreement	22188-Copyright assignment.pdf
Peer-review Report	22188-Peer-review(s).pdf
Scientific Misconduct Check	22188-Scientific misconduct check.pdf
Scientific Editor Work List	22188-Scientific editor work list.pdf