Publication Name	World Journal of Gastroenterology
Manuscript ID	2227
Country	Saudi Arabia

Received	2013-02-07 20:47
Peer-Review Started	2013-02-10 20:45
To Make the First Decision	2013-04-03 09:08
Return for Revision	2013-04-09 20:18
Revised	2013-05-21 20:39
Second Decision	2013-06-18 14:53
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2013-06-19 00:55
Articles in Press
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2013-08-23 10:49
Publish the Manuscript Online	2013-09-14 11:17

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access
Copyright
Article Reprints	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Pharmacology & Pharmacy
Manuscript Type	Autobiography
Article Title	Protective effect of naringenin on acetic acid-induced ulcerative colitis in rats
Manuscript Source	Invited Manuscript
All Author List	Salim S Al-Rejaie, Hatem M Abuohashish, Maher M Al-Enazi, Abdullah H Al-Assaf, Mihir Y Parmar and Mohammed M Ahmed
Funding Agency and Grant Number	Funding Agency Grant Number Deanship of Scientific Research at King Saud University for its funding this research through the research group project RGP-VPP-266
Corresponding Author	Salim S Al-Rejaie, Associate Professor of Pharmacology and Toxicology, Department of Pharmacology and Toxicology, College of Pharmacy, King Saud University, PO Box 55760, Riyadh 11544, Saudi Arabia. rejaie@ksu.edu.sa
Key Words	Naringenin; Ulcerative colitis; Inflammatory bowel disease; Oxidative stress
Core Tip	Inflammatory bowel disease (IBD), consisting of Crohn's disease (CD) and ulcerative colitis (UC), results in substantial morbidity and is difficult to treat. New strategies for adjunct therapies are needed. Systemic corticosteroids are highly effective at inducing clinical remission in cases of acute exacerbation of CD and UC; however, their use is limited by their frequent and sometimes severe side effects. Results of present study revealed that, naringenin has protective effects against acetic acid-induced UC by inhibiting inflammatory and oxidative bio-markers. Thus, it may pose promising outcomes for future clinical usage as a natural non-toxic effective supplement in IBD.
Publish Date	2013-09-14 11:17
Citation	Al-Rejaie SS, Abuohashish HM, Al-Enazi MM, Al-Assaf AH, Parmar MY, Ahmed MM. Protective effect of naringenin on acetic acid-induced ulcerative colitis in rats. World J Gastroenterol 2013; 19(34): 5633-5644
URL	http://www.wjgnet.com/1007-9327/full/v19/i34/5633.htm
DOI	http://dx.doi.org/10.3748/wjg.v19.i34.5633

Full Article (PDF)	WJG-19-5633.pdf
Manuscript File	2227-Review.docx
Answering Reviewers	2227-Answering reviewers.doc
Copyright License Agreement	2227-Copyright assignment.pdf
Non-Native Speakers of English Editing Certificate	2227-Language certificate.pdf
Peer-review Report	2227-Peer review(s).pdf
Scientific Editor Work List	2227-Scientific editor work list.doc