Publication Name	World Journal of Critical Care Medicine
Manuscript ID	22474
Country	Estonia

Received	2015-08-29 15:59
Peer-Review Started	2015-09-06 16:28
To Make the First Decision	2015-10-27 10:48
Return for Revision	2015-10-30 10:13
Revised	2015-11-18 07:47
Second Decision	2015-11-23 18:02
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2015-12-04 16:27
Articles in Press
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2016-01-15 08:28
Publish the Manuscript Online

ISSN	2220-3141(online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright	© The Author(s) 2016. Published by Baishideng Publishing Group Inc. All rights reserved.
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Category	Critical Care Medicine
Manuscript Type	Minireviews
Article Title	Mild to moderate intra-abdominal hypertension: Does it matter?
Manuscript Source	Invited Manuscript
All Author List	Liivi Maddison, Joel Starkopf and Annika Reintam Blaser
Funding Agency and Grant Number
Corresponding Author	Annika Reintam Blaser, MD, PhD, Department of Anaesthesiology and Intensive Care, University of Tartu, Puusepa 8, 51014 Tartu, Estonia. annika.reintam.blaser@ut.ee
Key Words	Intra-abdominal pressure; Intra-abdominal hypertension; Pathophysiology; Epidemiology; Severity; Treatment
Core Tip	This review summarizes the epidemiology, pathophysiological consequences and impact on outcome of mild to moderate intra-abdominal hypertension (IAH) and focuses on tasks for future research in the field. More than half of IAH patients present with IAH Grade Ⅰ and approximately a quarter with IAH grade Ⅱ. Even mild IAH can have a negative impact on tissue perfusion and be associated with impaired clinical outcomes. However, the impact of IAH and its different grades on mortality is controversial. Clear triggers for interventions in different patient groups with mild to moderate IAH are not defined.
Publish Date
Citation	Maddison L, Starkopf J, Reintam Blaser A. Mild to moderate intra-abdominal hypertension: Does it matter? World J Crit Care Med 2016; 5(1): 96-102
URL	http://www.wjgnet.com/2220-3141/full/v5/i1/96.htm
DOI	http://dx.doi.org/10.5492/wjccm.v5.i1.96

Full Article (PDF)	WJCCM-5-96.pdf
Full Article (Word)	WJCCM-5-96.doc
Manuscript File	22474-Review.docx
Answering Reviewers	22474-Answering reviewers.pdf
Audio Core Tip	22474-Audio core tip.mp3
Conflict-of-Interest Disclosure Form	22474-Conflict-of-interest statement.pdf
Copyright License Agreement	22474-Copyright assignment.pdf
Non-Native Speakers of English Editing Certificate	22474-Language certificate.pdf
Peer-review Report	22474-Peer-review(s).pdf
Scientific Misconduct Check	22474-Scientific misconduct check.pdf
Scientific Editor Work List	22474-Scientific editor work list.pdf