Publication Name	World Journal of Gastrointestinal Pathophysiology
Manuscript ID	22518
Country	Australia

Received	2015-09-01 09:19
Peer-Review Started	2015-09-02 10:19
To Make the First Decision	2015-09-28 12:20
Return for Revision	2015-09-29 09:25
Revised	2015-11-13 14:35
Second Decision	2015-12-17 18:40
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2016-01-04 17:09
Articles in Press	2016-01-04 17:09
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2016-01-23 16:45
Publish the Manuscript Online	2016-01-31 16:11

ISSN	2150-5330 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright	© The Author(s) 2016. Published by Baishideng Publishing Group Inc. All rights reserved.
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Website	http://www.wjgnet.com

Category	Gastroenterology & Hepatology
Manuscript Type	Diagnostic Advances
Article Title	Current application of proteomics in biomarker discovery for inflammatory bowel disease
Manuscript Source	Invited Manuscript
All Author List	Patrick PY Chan, Valerie C Wasinger and Rupert W Leong
Funding Agency and Grant Number
Corresponding Author	Rupert W Leong, MD, MBBS, Gastroenterology and Liver Services, Concord Repatriation General Hospital, Hospital Road, Concord, NSW 2137, Australia. rupert.leong@sswahs.nsw.gov.au
Key Words	Proteomics; Inflammatory bowel disease; Biomarkers; Molecular diagnostic techniques; Mass spectrometry
Core Tip	Proteomic methods provide a powerful tool that can be applied to the discovery of disease markers, allowing for rapid identification and quantification of proteins. Inflammatory bowel disease (IBD) currently faces many challenges, ranging from the elucidation of its pathophysiology to the accurate diagnosis in patients. Proteomics has been widely employed in many disease in the search of biomarkers, particularly cancer proteins. It has great potential to improve both our understanding and clinical management of IBD. Our review summarises the current application of proteomics to IBD and discusses challenges relating to translation into clinical practice.
Publish Date	2016-01-31 16:11
Citation	Chan PPY, Wasinger VC, Leong RW. Current application of proteomics in biomarker discovery for inflammatory bowel disease. World J Gastrointest Pathophysiol 2016; 7(1): 27-37
URL	http://www.wjgnet.com/2150-5330/full/v7/i1/27.htm
DOI	http://dx.doi.org/10.4291/wjgp.v7.i1.27

Full Article (PDF)	WJGP-7-27.pdf
Full Article (Word)	WJGP-7-27.doc
Manuscript File	22518-Review.docx
Answering Reviewers	22518-Answering reviewers.pdf
Audio Core Tip	22518-Audio core tip.mp3
Conflict-of-Interest Disclosure Form	22518-Conflict-of-interest statement.pdf
Copyright License Agreement	22518-Copyright assignment.pdf
Peer-review Report	22518-Peer-review(s).pdf
Scientific Misconduct Check	22518-Scientific misconduct check.pdf
Scientific Editor Work List	22518-Scientific editor work list.pdf