Publication Name	World Journal of Psychiatry
Manuscript ID	23174
Country	United States

Received	2015-10-27 08:56
Peer-Review Started	2015-11-03 09:42
To Make the First Decision	2015-12-04 11:18
Return for Revision	2015-12-04 16:29
Revised	2015-12-18 01:49
Second Decision	2016-01-18 10:36
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2016-01-29 17:53
Articles in Press	2016-01-29 17:54
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2016-03-04 10:09
Publish the Manuscript Online	2016-03-16 12:23

ISSN	2220-3206 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright	© The Author(s) 2016. Published by Baishideng Publishing Group Inc. All rights reserved.
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Category	Psychiatry
Manuscript Type	Review
Article Title	Cortical and subcortical gamma amino acid butyric acid deficits in anxiety and stress disorders: Clinical implications
Manuscript Source	Invited Manuscript
All Author List	Andrew W Goddard
Funding Agency and Grant Number
Corresponding Author	Andrew W Goddard, MD, Professor of Psychiatry, Department of Psychiatry, UCSF Fresno Medical Education Program, 155 N. Fresno Street, Fresno, CA 93701, United States. agoddard@fresno.ucsf.edu
Key Words	Brain imaging; Anxiogenesis; Gamma amino acid butyric acid; Anxiety disorders; Anxiolysis
Core Tip	Preclinical and clinical studies strongly support the notion that impairments in gamma amino acid butyric acid (GABA) neurotransmission underpin human stress and anxiety disorders. Measurement of in-vivo brain GABA function with modern neuroimaging tools, such as proton magnetic resonance spectroscopy, in healthy and disease populations, has contributed greatly to this literature, and also offers the possibility of monitoring GABAergic anxiolytic therapy.
Publish Date	2016-03-16 12:23
Citation	Goddard AW. Cortical and subcortical gamma amino acid butyric acid deficits in anxiety and stress disorders: Clinical implications. World J Psychiatr 2016; 6(1): 43-53
URL	http://www.wjgnet.com/2220-3206/full/v6/i1/43.htm
DOI	http://dx.doi.org/10.5498/wjp.v6.i1.43

Full Article (PDF)	WJP-6-43.pdf
Full Article (Word)	WJP-6-43.doc
Manuscript File	23174-Review.docx
Answering Reviewers	23174-Answering reviewers.pdf
Audio Core Tip	23174-Audio core tip.mp3
Conflict-of-Interest Disclosure Form	23174-Conflict-of-interest statement.pdf
Copyright License Agreement	23174-Copyright assignment.pdf
Peer-review Report	23174-Peer-review(s).pdf
Scientific Misconduct Check	23174-Scientific misconduct check.pdf
Scientific Editor Work List	23174-Scientific editor work list.pdf