Publication Name	World Journal of Transplantation
Manuscript ID	23280
Country	Spain

Received	2015-11-06 09:04
Peer-Review Started	2015-11-06 11:42
To Make the First Decision	2015-12-04 10:53
Return for Revision	2015-12-07 11:44
Revised	2015-12-22 17:20
Second Decision	2015-12-29 11:32
Accepted by Journal Editor-in-Chief	2015-12-29 19:28
Accepted by Company Editor-in-Chief	2016-01-07 17:07
Articles in Press	2016-01-07 17:08
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2016-03-04 11:59
Publish the Manuscript Online	2016-03-18 14:28

ISSN	2220-3230 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright	© The Author(s) 2016. Published by Baishideng Publishing Group Inc. All rights reserved.
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Category	Transplantation
Manuscript Type	Minireviews
Article Title	Immunosuppressive potency of mechanistic target of rapamycin inhibitors in solid-organ transplantation
Manuscript Source	Unsolicited Manuscript
All Author List	Alberto Baroja-Mazo, Beatriz Revilla-Nuin, Pablo Ramírez and José A Pons
Funding Agency and Grant Number	Funding Agency Grant Number Novartis España Principal Investigator from Instituto Salud Carlos III PI12/02042(to Pons JA)
Corresponding Author	José A Pons, MD, PhD, Division of Gastroenterology and Hepatology and Liver Transplant Unit, University Hospital Virgen de la Arrixaca, Ctra, Madrid-Cartagena s/n, 30120 Murcia, Spain. joseapons.imib.arrixaca@gmail.com
Key Words	Everolimus; Immunosuppression; Mechanistic target of rapamycin inhibitor; Rapamycin; Tolerance
Core Tip	Inhibitors of mechanistic target of rapamycin (mTOR), rapamycin and its derivative everolimus, have been used as immunosuppressive drugs during the last decade. Several reviews have been written on the use of these drugs compared to classical calcineurin inhibitors, however few has been reviewed about immunosuppressive potency of such compounds. Our aim is to summarize the principal studies about potency of the immunosuppressants, highlighting the studies carried out with inhibitors of mTOR.
Publish Date	2016-03-18 14:28
Citation	Baroja-Mazo A, Revilla-Nuin B, Ramírez P, Pons JA. Immu­nosuppressive potency of mechanistic target of rapamycin inhibitors in solid-organ transplantation. World J Transplant 2016; 6(1): 183-192
URL	http://www.wjgnet.com/2220-3230/full/v6/i1/183.htm
DOI	http://dx.doi.org/10.5500/wjt.v6.i1.183

Full Article (PDF)	WJT-6-183.pdf
Full Article (Word)	WJT-6-183.doc
Manuscript File	23280-Review.docx
Answering Reviewers	23280-Answering reviewers.pdf
Audio Core Tip	23280-Audio core tip.m4a
Conflict-of-Interest Disclosure Form	23280-Conflict-of-interest statement.pdf
Copyright License Agreement	23280-Copyright assignment.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s)	23280-Grant application form(s).pdf
Non-Native Speakers of English Editing Certificate	23280-Language certificate.pdf
Peer-review Report	23280-Peer-review(s).pdf
Journal Editor-in-Chief Review Report	23280-Journal editor-in-chief review report.pdf
Scientific Misconduct Check	23280-Scientific misconduct check.pdf
Scientific Editor Work List	23280-Scientific editor work list.pdf