Publication Name	World Journal of Clinical Cases
Manuscript ID	23291
Country	Japan

Received	2015-11-07 13:10
Peer-Review Started	2015-11-09 09:49
To Make the First Decision	2015-12-18 11:38
Return for Revision	2015-12-21 13:58
Revised	2016-01-12 17:11
Second Decision	2016-01-22 15:13
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2016-01-31 14:35
Articles in Press	2016-01-31 14:35
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2016-03-03 18:51
Publish the Manuscript Online	2016-03-11 09:54

ISSN	2307-8960 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright	© The Author(s) 2016. Published by Baishideng Publishing Group Inc. All rights reserved.
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Category	Gastroenterology & Hepatology
Manuscript Type	Case Report
Article Title	Combination therapy with daclatasvir and asunaprevir for dialysis patients infected with hepatitis C virus
Manuscript Source	Unsolicited Manuscript
All Author List	Ken Sato, Yuichi Yamazaki, Tatsuya Ohyama, Takeshi Kobayashi, Norio Horiguchi, Satoru Kakizaki, Motoyasu Kusano and Masanobu Yamada
Funding Agency and Grant Number
Corresponding Author	Ken Sato, MD, PhD, Department of Medicine and Molecular Science, Gunma University Graduate School of Medicine, 3-39-22 Showa-machi, Maebashi, Gunma 371-8511, Japan. satoken@gunma-u.ac.jp
Key Words	Hepatitis C; Oral drug; Daclatasvir; Asuna­previr; Dialysis
Core Tip	Oral combination therapy with the direct-acting antiviral agents daclatasvir and asunaprevir, which are both metabolized largely in the liver, is a very useful strategy for dialysis patients infected with genotype 1b hepatitis C virus. Although there were only 4 dialysis patients, the combination therapy was effective and showed a relatively favorable safety profile. One patient was admitted for heart failure with or without pneumonitis and percutaneous coronary intervention, although the causal relationship between these adverse events and the combination therapy was interpreted as negative. Our case reports warrant further studies, although careful observation during the treatment is needed.
Publish Date	2016-03-11 09:54
Citation	Sato K, Yamazaki Y, Ohyama T, Kobayashi T, Horiguchi N, Kakizaki S, Kusano M, Yamada M. Combination therapy with daclatasvir and asunaprevir for dialysis patients infected with hepatitis C virus. World J Clin Cases 2016; 4(3): 88-93
URL	http://www.wjgnet.com/2307-8960/full/v4/i3/88.htm
DOI	http://dx.doi.org/10.12998/wjcc.v4.i3.88

Full Article (PDF)	WJCC-4-88.pdf
Full Article (Word)	WJCC-4-88.doc
Manuscript File	23291-Review.docx
Answering Reviewers	23291-Answering reviewers.pdf
Audio Core Tip	23291-Audio core tip.MP3
Conflict-of-Interest Disclosure Form	23291-Conflict-of-interest statement.pdf
Copyright License Agreement	23291-Copyright assignment.pdf
Signed Informed Consent Form(s) or Document(s)	Informed_Consent_Statement_20151106210839.pdf
Institutional Review Board Approval Form or Document	23291-Institutional review board statement.pdf
Non-Native Speakers of English Editing Certificate	23291-Language certificate.pdf
Peer-review Report	23291-Peer-review(s).pdf
Scientific Misconduct Check	23291-Scientific misconduct check.pdf
Scientific Editor Work List	23291-Scientific editor work list.pdf