Publication Name	World Journal of Gastroenterology
Manuscript ID	23556
Country	China

Received	2015-12-01 08:50
Peer-Review Started	2015-12-01 17:25
To Make the First Decision	2015-12-21 15:16
Return for Revision	2015-12-22 09:16
Revised	2016-01-19 13:01
Second Decision	2016-01-21 08:54
Accepted by Journal Editor-in-Chief	2016-01-23 12:09
Accepted by Executive Editor-in-Chief	2016-01-30 17:31
Articles in Press	2016-01-30 17:32
Publication Fee Transferred
Edit the Manuscript by Language Editor	2016-02-21 12:02
Typeset the Manuscript	2016-03-15 12:26
Publish the Manuscript Online	2016-03-23 16:22

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright	© The Author(s) 2016. Published by Baishideng Publishing Group Inc. All rights reserved.
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Website	http://www.wjgnet.com

Category	Gastroenterology & Hepatology
Manuscript Type	Meta-Analysis
Article Title	Helicobacter pylori eradication therapy for functional dyspepsia: Systematic review and meta-analysis
Manuscript Source	Unsolicited Manuscript
All Author List	Li-Jun Du, Bin-Rui Chen, John J Kim, Sarah Kim, Jin-Hua Shen and Ning Dai
Funding Agency and Grant Number
Corresponding Author	Ning Dai, MD, Professor, Department of Gastroenterology, Sir Run Run Shaw Hospital, Zhejiang University, No. 3 East Qingchun Road, Hangzhou 310020, Zhejiang Province, China. ndaicn@yahoo.com
Key Words	Functional dyspepsia; Helicobacter pylori eradication; Symptom improvement; Quality of life; Peptic ulceration; Meta-analysis
Core Tip	The decision to eradicate Helicobacter pylori (H. pylori) in patients with functional dyspepsia requires individual assessment. This meta-analysis suggests that H. pylori eradication therapy is beneficial for symptom relief, reduces the development of peptic ulceration, and leads to histologic resolution of chronic gastritis but does not improve the quality of life and may even result in adverse events. Otherwise, other validated treatment such as acid suppression, prokinetics, and psychiatric treatment should also be considered.
Publish Date	2016-03-23 16:22
Citation	Du LJ, Chen BR, Kim JJ, Kim S, Shen JH, Dai N. Helicobacter pylori eradication therapy for functional dyspepsia: Systematic review and meta-analysis. World J Gastroenterol 2016; 22(12): 3486-3495
URL	http://www.wjgnet.com/1007-9327/full/v22/i12/3486.htm
DOI	http://dx.doi.org/10.3748/wjg.v22.i12.3486

Full Article (PDF)	WJG-22-3486.pdf
Full Article (Word)	WJG-22-3486.doc
Manuscript File	23556-Review.docx
Answering Reviewers	23556-Answering reviewers.pdf
Audio Core Tip	23556-Audio core tip.mp3
Biostatistics Review Certificate	23556-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form	23556-Conflict-of-interest statement.pdf
Copyright License Agreement	23556-Copyright assignment.pdf
Peer-review Report	23556-Peer-review(s).pdf
Journal Editor-in-Chief Review Report	23556-Journal editor-in-chief review report.pdf
Scientific Misconduct Check	23556-Scientific misconduct check.pdf
Scientific Editor Work List	23556-Scientific editor work list.pdf