Publication Name	World Journal of Gastroenterology
Manuscript ID	23710
Country	Italy

Received	2015-12-12 15:15
Peer-Review Started	2015-12-12 20:33
To Make the First Decision	2015-12-30 16:47
Return for Revision	2015-12-31 14:23
Revised	2015-12-31 19:03
Second Decision	2016-01-21 11:29
Accepted by Journal Editor-in-Chief	2016-01-21 15:56
Accepted by Executive Editor-in-Chief	2016-01-30 17:29
Articles in Press	2016-01-30 17:29
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2016-03-19 20:19
Publish the Manuscript Online	2016-04-19 09:42

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright	© The Author(s) 2016. Published by Baishideng Publishing Group Inc. All rights reserved.
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Category	Gastroenterology & Hepatology
Manuscript Type	Retrospective Study
Article Title	Lymphocyte-to-monocyte ratio predicts survival after radiofrequency ablation for colorectal liver metastases
Manuscript Source	Invited Manuscript
All Author List	Antonio Facciorusso, Valentina Del Prete, Nicola Crucinio, Gaetano Serviddio, Gianluigi Vendemiale and Nicola Muscatiello
Funding Agency and Grant Number
Corresponding Author	Antonio Facciorusso, MD, Gastro­enterology Unit, Department of Medical Sciences, University of Foggia, Viale L.Pinto, 1, 71100 Foggia, Italy. antonio.facciorusso@virgilio.it
Key Words	Colorectal liver metastasis; Radiofrequency ablation; Survival; Prognosis; Regression
Core Tip	This is a retrospective study to test the correlation between baseline lymphocyte-to-monocyte ratio (LMR) and survival outcomes in colorectal liver metastasis patients treated with radiofrequency ablation. Median overall survival (OS) was 55 mo in patients with LMR > 3.96% and 34 mo in patients with LMR ≤ 3.96% (P = 0.007). Time to recurrence (TTR) was 35 mo in the group > 3.96% and 25 mo in the group ≤ 3.96% (P = 0.02). Nodule size and LMR were the only significant predictors either for OS and for TTR in multivariate analysis. LMR was useful as clinical predictor of survival outcomes.
Publish Date	2016-04-19 09:42
Citation	Facciorusso A, Del Prete V, Crucinio N, Serviddio G, Vendemiale G, Muscatiello N. Lymphocyte-to-monocyte ratio predicts survival after radiofrequency ablation for colorectal liver metastases. World J Gastroenterol 2016; 22(16): 4211-4218
URL	http://www.wjgnet.com/1007-9327/full/v22/i16/4211.htm
DOI	http://dx.doi.org/10.3748/wjg.v22.i16.4211

Full Article (PDF)	WJG-22-4211.pdf
Full Article (Word)	WJG-22-4211.doc
Manuscript File	23710-Review.docx
Answering Reviewers	23710-Answering reviewers.pdf
Audio Core Tip	23710-Audio core tip.mp3
Biostatistics Review Certificate	23710-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form	23710-Conflict-of-interest statement.pdf
Copyright License Agreement	23710-Copyright assignment.pdf
Signed Informed Consent Form(s) or Document(s)	Informed_Consent_Statement_20151212031946.pdf
Institutional Review Board Approval Form or Document	23710-Institutional review board statement.pdf
Non-Native Speakers of English Editing Certificate	23710-Language certificate.pdf
Peer-review Report	23710-Peer-review(s).pdf
Journal Editor-in-Chief Review Report	23710-Journal editor-in-chief review report.pdf
Scientific Misconduct Check	23710-Scientific misconduct check.pdf
Scientific Editor Work List	23710-Scientific editor work list.pdf